Architecture and Cellular Composition of the Air-Blood Barrier

Details

• Personal Author:
  Crapo JD ; Gehr P ; Pinkerton KE
• Description:
  There are over 4000 different varieties of mammals. Among the terrestrial mammals, body size ranges from the 2-g shrew to the 6600-kg elephant. Lung tissue mass involved in gas exchange in this class of animal , also covers a wide spectrum. Differences in the dimensions of the mammalian respiratory system are intriguing, since those pulmonary tissues involved in gas exchange are strikingly similar in organization and cellular composition, yet serve vastly different oxygen consumption needs in a highly efficient manner for animals spanning more than a three million-fold difference in total body mass (Gehr et aI., 1981). The purpose of this chapter is to review and to compare the anatomy and cellular composition of the alveolar region in mammalian lungs. [Description provided by NIOSH]
• Subjects:
  Air Pollutants, Occupational Animals Dust Irritants Lung Lung Diseases Occupational Health Particulate Matter Respiratory Function Tests Respiratory Hypersensitivity Respiratory System Respiratory Tract Diseases Safety

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• Keywords:
  Airborne-dusts Airborne-fibers Alveolar-cells Animal-studies Cellular-function Cellular-reactions Cellular-respiration Cellular-structures Lung-burden Lung-cells Lung-disorders Lung-function Lung-irritants Respiratory-function-tests Respiratory-gas-analysis Respiratory-hypersensitivity Respiratory-irritants Respiratory-rate Respiratory-system-disorders

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• ISBN:
  9780849388392
• Publisher:
  CRC Press
• Document Type:
  Text
• Funding:
  Cooperative Agreement
• Genre:
  Book
• Place as Subject:
  California ; North Carolina ; OSHA Region 4 ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  121-128
• Volume:
  1
• NIOSHTIC Number:
  nn:20033783
• Citation:
  Treatise on Pulmonary Toxicology. Comparative Biology of the Normal Lung. Boca Raton. FL: CRC Press, 1992 Feb; 1:121-128
• Contact Point Address:
  K. E. Pinkerton, Department of Anatomy School of Veterinary Medicine University of California, Davis, CA 95616-8542
• Federal Fiscal Year:
  1992
• Performing Organization:
  University of California - Davis
• Peer Reviewed:
  False
• Start Date:
  19900930
• Source Full Name:
  Treatise on Pulmonary Toxicology. Comparative Biology of the Normal Lung
• End Date:
  20020929
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:a139b1379ebfaeb99b202b52994c740c92cbb39d3b0c80ad3bb2531f58f25398de8fd1fe55790d3cf22c3d244b355beec840f9415a046958b496365a8e636da5
• Download URL:
  https://stacks.cdc.gov/view/cdc/189227/cdc_189227_DS1.pdf
• File Type:
  [PDF - 967.12 KB ]