Pesticide Use and Chronic Bronchitis Among Farmers in the Agricultural Health Study

Details

• Personal Author:
  Alavanja MCR ; Henneberger, Paul K. ; Hoppin JA ; Kullman, Greg J. ; London SJ ; Sandler DP ; Umbach DM ; Valcin M
• Description:
  Background: Farmers have increased risk for chronic bronchitis. Few investigators have considered pesticides. Methods: We evaluated pesticides as risk factors for chronic bronchitis using the Agricultural Health Study enrollment data on lifetime pesticide use and history of doctor-diagnosed chronic bronchitis from 20,908 private pesticide applicators, primarily farmers. Results: A total of 654 farmers (3%) reported chronic bronchitis diagnosed after age 19. After adjustment for correlated pesticides as well as confounders, 11 pesticides were significantly associated with chronic bronchitis. Heptachlor use had the highest odds ratio (OR=1.50, 95% Confidence Interval (CI)=1.19, 1.89). Increased prevalence for chronic bronchitis was also seen for individuals who had a history of a high pesticide exposure event (OR=1.85, 95% CI=1.51, 2.25) and for those who also applied pesticides in off-farm jobs (OR=1.40, 95%CI=1.04, 1.88). Co-morbid asthma and current farm activities did not explain these results. Conclusions: These results provide preliminary evidence that pesticide use may increase chronic bronchitis prevalence. [Description provided by NIOSH]
• Subjects:
  Agriculture Asthma Asthma, Occupational Chlorine Compounds Chronic Disease Farmers Fungi Fungicide, Industrial Herbicides Insecticides Lung Lung Diseases Occupational Exposure Occupational Health Organophosphates Respiratory System Respiratory Tract Diseases Risk Assessment Risk Factors Safety

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• Keywords:
  Agricultural-chemicals Agricultural-workers Agricultural Exposures Author Keywords: Respiratory Disease Bronchial-asthma Chronic-inflammation Fumigants Fungicides Lung-disorders Lung-irritants Occupational-exposure Occupational Exposure Organo-chlorine-compounds Organo-phosphorus-pesticides Pesticides Pesticides-and-agricultural-chemicals Pulmonary-system-disorders Pyrethroids Respiratory-system-disorders Risk-analysis Risk-factors Statistical-analysis

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• ISSN:
  0271-3586
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Maryland ; North Carolina ; OSHA Region 3 ; OSHA Region 4 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DRDS - Division of Respiratory Disease Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  50
• Issue:
  12
• NIOSHTIC Number:
  nn:20033662
• Citation:
  Am J Ind Med 2007 Dec; 50(12):969-979
• Contact Point Address:
  Jane Hoppin, NIEHS, Epidemiology Branch, MD A3-05, P.O. Box 12233, ResearchTriangle Park, NC 27709-2233
• Email:
  hoppin1@niehs.nih.gov
• CAS Registry Number:
  Heptachlor (CAS RN 76-44-8)
• Federal Fiscal Year:
  2008
• Peer Reviewed:
  True
• Source Full Name:
  American Journal of Industrial Medicine
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:cbf0817807554ee026f3752a65e43ab034d24b10ff4fd0970d4bcc67b7442f905589d6d98db7333b694d423bbac62adec6c7ba05f2ddad5e4710b81e0a6d96e0
• Download URL:
  https://stacks.cdc.gov/view/cdc/189142/cdc_189142_DS1.pdf
• File Type:
  [PDF - 125.63 KB ]