Repetitive Finger Joint Flexion Without External Load Leads to Articular Cartilage Thinning in an In Vivo Rabbit Model

Details

• Personal Author:
  King KB ; Marecek GS ; Opel CF ; Rempel DM
• Description:
  Repetitive hand tasks are a risk factor for the development of musculoskeletal disorders, including degenerative joint disease [1,2]. Additionally, high occupational loads have been described as a risk factor for the development of osteoarthritis [3,4]. However, few studies have identified repetitive use independent of loading as a risk factor for joint injury. Thus, it remains unclear which component, repetition frequency or force, is primarily responsible for joint damage. To examine the difference in the effect of frequency vs. force, we have developed a novel in vivo animal model of cyclic joint loading [5]. In this model, the rabbit forepaw digits can be flexed with or without an added external load. This study compares the changes in articular cartilage thickness caused by repetition alone to those changes caused by repetition plus an external load. [Description provided by NIOSH]
• Subjects:
  Animals Biomechanical Phenomena Cumulative Trauma Disorders Laboratories Musculoskeletal Diseases Musculoskeletal System Occupational Health Safety
• Keywords:
  Animal-studies Biomechanics Cumulative-trauma Cumulative-trauma-disorders Hand-injuries In-vivo-studies Injuries Laboratory-animals Models Muscles Musculoskeletal-system Musculoskeletal-system-disorders Repetitive-work

  More +
• ISSN:
  0149-6433
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Abstract or Summary ; Proceedings
• Place as Subject:
  California ; Colorado ; OSHA Region 8 ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  52
• NIOSHTIC Number:
  nn:20033284
• Citation:
  Trans Annu Meet Orthop Res Soc 2006 Mar; 52:1898
• Email:
  kbking@itsa.ucsf.edu
• Federal Fiscal Year:
  2006
• NORA Priority Area:
  Disease and Injury: Musculoskeletal Disorders of the Upper Extremities
• Performing Organization:
  University of California - San Francisco
• Peer Reviewed:
  False
• Start Date:
  20010701
• Source Full Name:
  Transactions of the Annual Meeting of the Orthopaedic Research Society
• End Date:
  20060630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:5d004221dfe6088fe891b7631e0b082aeeff9909bca39165f66fb7aadea2588ccef84d8b290b99858536bc28d02987a3ec97fbe9ce918397019ed27c9de1a2df
• Download URL:
  https://stacks.cdc.gov/view/cdc/188926/cdc_188926_DS1.pdf
• File Type:
  [PDF - 81.37 KB ]