Methyl Jasmonate Enhances Antioxidant Activity and Flavonoid Content in Blackberries (Rubus sp.) and Promotes Antiproliferation of Human Cancer Cells

Details

• Personal Author:
  Bowman L ; Ding M ; Wang SY ; Bowman L ; Ding M ; Wang SY
• Description:
  The effects of preharvest methyl jasmonate (MJ) application on fruit quality, antioxidant activity and flavonoid content in blackberries (Rubus sp.) were determined. Anticancer activity against human lung A549 cells and HL-60 leukemia cells was also evaluated. Three blackberry cultivars (Chester Thornless, Hull Thornless and Triple Crown) were used in these experiments. Blackberries treated with MJ (0.01 and 0.1 mM) had higher soluble solids content, and lower titratable acids than untreated fruit as well as enhanced content of flavonoids and increased antioxidant capacity. Extracts of treated fruit showed enhanced inhibition of A549 cell and HL-60 cell proliferation and induced the apoptosis of HL-60 cells. Cultivar Hull Thornless had higher soluble solids and lower titratable acids compared to cv. Chester Thornless and Triple Crown. On the basis of fresh weight of fruit, Hull Thornless also had significantly higher anthocyanin, total phenolic content, antioxidant and antiproliferation activity than other two cultivars. [Description provided by NIOSH]
• Subjects:
  Agriculture Fungi Fungicide, Industrial Lung Occupational Health Respiratory System Safety
• Keywords:
  Agricultural-chemicals Agricultural-industry Agricultural-processes Antifungals Cell-biology Cell-function Cell-morphology Cellular-reactions Fungicides Leukocytes Lung-cells

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• ISSN:
  0308-8146
• Document Type:
  Text
• Genre:
  Journal Article ; Journal Article
• Place as Subject:
  Maryland ; OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH) ; National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division ; HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health ; Workplace Safety & Health
• Location:
  North America ; North America
• Volume:
  107
• Issue:
  3
• NIOSHTIC Number:
  nn:20033221
• Citation:
  Food Chem 2008 Apr; 107(3):1261-1269
• Contact Point Address:
  Shiow Y. Wang, Genetic Improvement of Fruit and Vegetable Laboratory, Beltsville Agricultural Research Center, Agricultural Research Service, US Department of Agriculture, Beltsville, MD 20705-2350
• Email:
  shiow.wang@ars.usda.gov
• CAS Registry Number:
  (-)-Methyl jasmonate (CAS RN 1211-29-6) ; (-)-Methyl jasmonate (CAS RN 1211-29-6)
• Federal Fiscal Year:
  2008
• Peer Reviewed:
  True
• Source Full Name:
  Food Chemistry
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:5e2c06c7748bc2b8f905c0fe073922f4c966138ee2635f9200aec07eb2f96257066493122d69a4e099bc79a684577647c73db351f5e34f82b44bb172d8c76e62
• Download URL:
  https://stacks.cdc.gov/view/cdc/188878/cdc_188878_DS1.pdf
• File Type:
  [PDF - 206.33 KB ]