Design, Conduct and Analysis of Surveys on Work-Related Asthma

Details

• Personal Author:
  Heederik D ; Kreiss, Kathleen
• Description:
  Surveys on work-related asthma serve public health investigation, research on exposure-response relations, screening for pre-clinical disease, and demonstrations of effectiveness of interventions. Hypotheses dictate survey design, which include cross-sectional, case-control, cohort, and intervention studies. Tools for characterizing medical risk factors and outcomes include questionnaires, spirometry, tests of bronchial hyperreactivity, exhaled indices, induced sputum, immunological tests, and nasal inflammatory indices. An important component of surveys is exposure assessment to compare a population to existing literature and other surveys with attention to exposure level, range, and variability among workers. Allergen exposures are challenging to characterize with respect to peak exposures and evolving immunochemical measurement methods. Exposure assessment strategies are developing rapidly for analysis of exposure-response relationships, whether for sensitization to allergens or for respiratory symptoms or diagnoses. Power calculations should guide decisions about whether to implement surveys. Research needs include surveys of populations with irritant or neutrophillic asthma and populations in damp buildings. The relevance of dermal exposure to sensitizers requires examination as a risk factor for asthma. New causes of work-related asthma may be identified by surveying industries with excess asthma in population-based studies that do not have recognized causes of asthma. [Description provided by NIOSH]
• Subjects:
  Asthma Asthma, Occupational Environmental Monitoring Hypersensitivity Irritants Occupational Exposure Occupational Health Respiratory System Respiratory Tract Diseases Safety Workplace

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• Keywords:
  Allergens Allergic-disorders Allergic-reactions Bronchial-asthma Exposure-assessment Occupational-exposure Occupational-respiratory-disease Pulmonary-system-disorders Respiratory-irritants Respiratory-system-disorders Surveillance-programs Work-environment

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• ISBN:
  9783764385552
• Publisher:
  Birkhauser
• Document Type:
  Text
• Genre:
  Book
• Place as Subject:
  OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DRDS - Division of Respiratory Disease Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  327-353
• NIOSHTIC Number:
  nn:20036960
• Citation:
  Occupational asthma. Sigsgaard T, Heederik D, eds. Basel, Switzerland: Birkhauser, 2010 Jun; :327-353
• Editor(s):
  Sigsgaard T; Heederik D
• Federal Fiscal Year:
  2010
• Peer Reviewed:
  False
• Source Full Name:
  Occupational asthma
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:31b00f0fe4a9ef91d1bb0732098939b775526d97570e317355e17ebb6bd23f162df43481c934298f22658dd0529705766e3083b5be9fe219f6261539844c8d5d
• Download URL:
  https://stacks.cdc.gov/view/cdc/188157/cdc_188157_DS1.pdf
• File Type:
  [PDF - 1.17 MB ]