Occupational Rhinosinusitis and Upper Airway Disease: The World Trade Center Experience

Details

• Personal Author:
  Cohen JM ; de la Hoz RE ; Shohet MR
• Description:
  The World Trade Center disaster and its recovery work involved a range of hazardous occupational exposures that have not been fully characterized but that can be reasonably assumed to have the potential to cause mucosal inflammation, preferentially (but not exclusively) in the upper airway. A high prevalence of rhinosinusitis and upper airway disease (UAD) symptoms was reported by several early surveys. Clinical studies demonstrated objective, clinically significant, and persistent chronic perennial rhinosinusitis and UAD-with or without seasonal exacerbation-in a large proportion of patients. Demonstration of an association between UAD and available exposure indicators has been limited. Atopy seemed to be associated with increased UAD symptom severity and to be a risk factor for upper, but not lower, airway disease. World Trade Center-related UAD is considered an irritant-induced disease but not, in many cases, of acute onset. No data thus far suggest an increased upper airway cancer incidence. [Description provided by NIOSH]
• Subjects:
  Environmental Monitoring Hypersensitivity Irritants Lung Lung Diseases Occupational Exposure Occupational Health Respiratory Hypersensitivity Respiratory System Respiratory Tract Diseases Safety Workplace

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• Keywords:
  Allergens Allergy Atopy Author Keywords: Occupational Medicine Exposure-assessment Exposure-levels Exposure-methods Inhalation-studies Inhalation Injury Laryngitis Lung-disorders Occupational-exposure Occupational-hazards Occupational-health Occupational-respiratory-disease Pharyngitis Pulmonary-system-disorders Reflux Disease Respiratory-hypersensitivity Respiratory-infections Respiratory-irritants Respiratory-system-disorders Rhinitis Sinusitis Statistical-analysis Work-areas Work-environment Work-operations Work-performance Worker-health

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• ISSN:
  1529-7322
• Document Type:
  Text
• Funding:
  Cooperative Agreement
• Genre:
  Journal Article
• Place as Subject:
  New York ; OSHA Region 2
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  77-83
• Volume:
  10
• Issue:
  2
• NIOSHTIC Number:
  nn:20036761
• Citation:
  Curr Allergy Asthma Rep 2010 Mar; 10(2):77-83
• Contact Point Address:
  Rafael E. de la Hoz, Mount Sinai School of Medicine, Department of Preventive Medicine, One Gustave L. Levy Place, Box 1059, New York, NY 10029
• Email:
  rafael.delahoz@mssm.edu
• Federal Fiscal Year:
  2010
• NORA Priority Area:
  Services
• Performing Organization:
  Mount Sinai School of Medicine of New York University
• Peer Reviewed:
  True
• Start Date:
  20040715
• Source Full Name:
  Current Allergy & Asthma Reports
• End Date:
  20090714
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:197f9e428ba88232cca4061b82af325afeeacdfb5f88ba511ae4809831a575c0a59fdd5f7dcd320194d8e9e337bf0939463400230481fe4fde2d7517a8e88911
• Download URL:
  https://stacks.cdc.gov/view/cdc/188053/cdc_188053_DS1.pdf
• File Type:
  [PDF - 269.09 KB ]