Latex as a Significant Source of Hevea brasiliensis Allergen Exposure

Details

• Personal Author:
  Beezhold, Donald H. ; Hamilton, Robert G. ; Horton K ; Kostyal D ; Lockwood S
• Description:
  The prevalence of allergic reactions to Hevea brasiliensis natural rubber latex among high-risk health care workers and patients undergoing multiple surgical procedures has diminished from epidemic levels in the mid-1990s. This decrease is attributed to avoidance of powdered latex medical gloves and improved quality control in the manufacturing process. However, sensitization to Hevea allergens continues through exposure to less well established sources. To document this phenomenon, we used 3 standardized methods approved by the American Society for Testing Materials (ASTM) to quantify the total protein (ASTM Standard Test Method for Analysis of Aqueous Extractable Protein in Natural Rubber and Its Products Using the Modified Lowry Method, 2005), Hevea antigen (ASTM Standard Test Method for the Immunological Measurement of Antigenic Protein in Natural Rubber and Its Products, 2007), and Hevea allergen (ASTM Standard Test Method for Immunological Measurement of Four Principal Allergenic Proteins in Natural Rubber and Its Products Derived From Latex, 2008 content in natural rubber latex toy balloons, dental dams, medical gloves, and nitrile and guayule medical gloves (negative controls). Although previous studies examined allergen/antigen content in rubber medical products, this study simultaneously investigated Hevea levels in balloons, dental dams, and glove products using the 3-tier ASTM test protocol. [Description provided by NIOSH]
• Subjects:
  Environmental Monitoring Health Personnel Hypersensitivity Occupational Exposure Occupational Health Risk Assessment Risk Factors Safety Workplace
• Keywords:
  Allergens Allergic-disorders Allergic-reactions Allergies Exposure-assessment Exposure-levels Exposure-methods Health-care-personnel Occupational-hazards Occupational-health Quantitative-analysis Risk-analysis Risk-factors Statistical-analysis Work-analysis Work-environment Work-operations Work-practices Workplace-studies

  More +
• ISSN:
  1081-1206
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Maryland ; OSHA Region 3 ; Pennsylvania ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  354-355
• Volume:
  103
• Issue:
  4
• NIOSHTIC Number:
  nn:20036412
• Citation:
  Ann Allergy Asthma Immunol 2009 Oct; 103(4):354-355
• Email:
  kostyal_david@guthrie.org
• Federal Fiscal Year:
  2010
• Peer Reviewed:
  False
• Source Full Name:
  Annals of Allergy, Asthma and Immunology
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:13c82bbd34945015268ae488de6159b22f415669f83aa5699c540f3811c1b341ab33ce4d37f728c79661fb467d2dc1737e2fad5169478c7c3f1785ca445a044e
• Download URL:
  https://stacks.cdc.gov/view/cdc/187855/cdc_187855_DS1.pdf
• File Type:
  [PDF - 173.61 KB ]