Numerical Simulations Investigating the Regional and Overall Deposition Efficiency of the Human Nasal Cavity

Details

• Personal Author:
  Ahmadi G ; Cheng YS ; Hopke PK ; Shanley KT ; Zamankhan P
• Description:
  Numerical simulations have been carried out on a model of the right passageway of an anonymous, adult male's nasal cavity, constructed from magnetic resonance imagery (MRI) scans. Steady, laminar, inspiratory flow was assumed to simulate inhalation. Analysis shows smoothly varying streamlines with a peak in velocity magnitude occurring in the nasal valves and a peak in vorticity magnitude immediately posterior. Dilute, uniform concentrations of inertial (1 microm < or = d(ae) < or = 10 microm) particles were released at the nostril and tracked via a Lagrangian tracking algorithm. Deposition efficiency is shown to increase with particle size and flow rate. Preferential deposition is seen in the anterior third of the nasal cavity for large Stokes number particles. An empirical expression for particle deposition is proposed that incorporates particle size, flow rate, and nose anatomy. Description provided by NIOSH
• Subjects:
  • Aerosols
  • Air Movements
  • Air Pollutants, Occupational
  • Air Pollution
  • Air Pollution, Indoor
  • Dust
  • Environmental Monitoring
  • Ergonomics
  • Irritants
  • Laboratories
  More +
• Keywords:
  • Aerosol-particles
  • Aerosols
  • Air-contamination
  • Air-flow
  • Air-monitoring
  • Air-quality
  • Air-sampling
  • Air-sampling-techniques
  • Breathing
  • Ergonomics
  More +
• ISSN:
  0895-8378
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  New Mexico ; OSHA Region 6
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  20
• Issue:
  12
• NIOSHTIC Number:
  nn:20035420
• Citation:
  Inhal Toxicol 2008 Sep; 20(12):1093-1100
• Contact Point Address:
  Prof. Goodarz Ahmadi, Clarkson University, Department of Mechanical and Aeronautical Engineering, 8 Clarkson Avenue, Potsdam, NY 13699-5700
• Email:
  ahmadi@clarkson.edu
• Federal Fiscal Year:
  2008
• Performing Organization:
  Lovelace Biomedical & Environmental Research
• Peer Reviewed:
  True
• Start Date:
  20020901
• Source Full Name:
  Inhalation Toxicology
• End Date:
  20080831
• Download URL:
  https://stacks.cdc.gov/view/cdc/187282/cdc_187282_DS1.pdf
• File Type:
  [PDF - 2.80 MB]
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:e3c8226be9214b2e63ccf8946f4e96f966024173cbd257f72f39455ee038c3383c562c4870f2541c85cca3ad72fd4893444d6af1b10d0ec01844d8f45c9fe79e