Cumulative Sensitization and Disease in a Beryllium Oxide Ceramics Worker Cohort

Details

• Personal Author:
  Deubner, David C. ; Henneberger, Paul K. ; Kitt MM ; Kreiss, Kathleen ; Schuler, Christine R.
• Description:
  Objective: We followed a cohort of 136 beryllium oxide ceramics workers from 1992 to 2003, including those who left employment, for beryllium sensitization and chronic beryllium disease (CBD), Methods: We invited the cohort's participation in current worker surveys in 1992, 1998, 2000, and 2002-2003, and in former worker surveys in 2000-2001 and 2003. We calculated 11-year cumulative incidences (after 1992 initial survey) of sensitization and CBD, both crude and corrected for interval censoring; and period prevalences (including 1992 findings), crude and corrected. Results: In 1992, point prevalences were 6 sensitized and 4% CBD. We obtained follow-up on 83% of 128 not sensitized in 1992. Crude cumulative incidences for sensitization and CBD were 13% and 9%, respectively; corrected were 15% and 11%. Crude period prevalences for sensitization and CBD were 16% and 11%, respectively; corrected were 20% and 14%. Corrected period prevalences for pre-1992 machining work were 30% and 20%. Conclusions: With repeated testing over 11 years, total sensitization and CBD in this cohort were triple initial 1992 survey results. [Description provided by NIOSH]
• Subjects:
  Ceramics Chemistry Hypersensitivity Manufacturing And Industrial Facilities Occupational Diseases Occupational Exposure Occupational Health Safety
• Keywords:
  Ceramic-materials Ceramics-industry Chemical-hypersensitivity Chemical-industry-workers Chemical-processing Chemical-properties Chemical-synthesis Occupational-diseases Occupational-exposure Occupational-health Statistical-analysis Worker-health

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• ISSN:
  1076-2752
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Georgia ; Ohio ; OSHA Region 3 ; OSHA Region 4 ; OSHA Region 5 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DRDS - Division of Respiratory Disease Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  50
• Issue:
  12
• NIOSHTIC Number:
  nn:20034870
• Citation:
  J Occup Environ Med 2008 Dec; 50(12):1343-1350
• Contact Point Address:
  Christine R. Schuler, PhD, Division of Respiratory Disease Studies, Field Studies Branch, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, 1095 Willowdale Road, MS H2800, Morgantown, WV 26505
• Email:
  christine.schuler@cdc.hhs.gov
• CAS Registry Number:
  Beryllium (CAS RN 7440-41-7)
• Federal Fiscal Year:
  2009
• Peer Reviewed:
  True
• Source Full Name:
  Journal of Occupational and Environmental Medicine
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:999690e8f75bdd11462669215f58058ac63bd9d8c1e9a70874996e943d7c306790438e79284793c10aeb78240e12affca31fb74f7e4da9a27fd1aac0754c7d70
• Download URL:
  https://stacks.cdc.gov/view/cdc/186916/cdc_186916_DS1.pdf
• File Type:
  [PDF - 219.37 KB ]