Systematic Literature Review of Uses and Levels of Occupational Exposure to Tetrachloroethylene

Details

• Personal Author:
  De Roos AJ ; Gold LS ; Stewart P ; Waters M
• Description:
  Tetrachloroethylene has been one of the most widely used chlorinated solvents in the United States. This review provides a basis for tetrachloroethylene exposure assessment in population-based case-control studies. We performed literature searches in MEDLINE, TOXLINE, NIOSHTIC, and the NIOSH Health Hazard Evaluation databases using relevant search terms. We calculated weighted arithmetic means from the measurement data and compiled these into three summary tables by type of operation: (1) dry cleaning, (2) degreasing, and (3) other operations. We identified 258 relevant documents, of which 179 (69%) contained useful descriptive information. Within the dry cleaning industry, the overall arithmetic mean (AM) for personal tetrachloroethylene exposures was 59 ppm (range: 0-4636, n = 1395). Machine operators who transferred wet garments to a dryer had the highest levels (AM = 150 ppm [range: 0-1000, n = 441]) of the jobs in this industry. The AM for personal measurements associated with degreasing was 95 ppm (range: 0-1800, n = 206). In addition, we identified several other sources of substantial tetrachloroethylene exposure, including cleaning mining equipment, testing coal, cleaning animal coats in taxidermy, and cleaning and duplicating film. Exposure assessment in population-based, case-control studies is a complex process requiring substantial resources. Researchers conducting these types of studies will be able to use results of the measurements to quantify tetrachloroethylene exposure levels for various jobs. [Description provided by NIOSH]
• Subjects:
  Chemistry Environmental Exposure Environmental Pollution Hypersensitivity Occupational Exposure Occupational Health Risk Assessment Risk Factors Safety Workplace
• Keywords:
  Biological-effects Biological-monitoring Chemical-cleaning Chemical-hypersensitivity Chemical-properties Environmental-pollution Mathematical-models Models Occupational-exposure Physiological-chemistry Physiological-response Physiopathology Quantitative-analysis Risk-analysis Risk-factors Work-analysis Work-environment Worker-health Workplace-monitoring Workplace-studies

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• ISSN:
  1545-9624
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Ohio ; OSHA Region 10 ; OSHA Region 3 ; OSHA Region 5 ; Virginia ; Washington
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  5
• Issue:
  12
• NIOSHTIC Number:
  nn:20034653
• Citation:
  J Occup Environ Hyg 2008 Dec; 5(12):807-839
• Contact Point Address:
  Laura S. Gold, Department of Epidemiology, University of Washington, Seattle, Washington 98195
• Email:
  lgold@fhcrc.org
• CAS Registry Number:
  Tetrachloroethylene (CAS RN 127-18-4)
• Federal Fiscal Year:
  2009
• Performing Organization:
  University of Washington
• Peer Reviewed:
  True
• Start Date:
  20050701
• Source Full Name:
  Journal of Occupational and Environmental Hygiene
• End Date:
  20250630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:0ae20521223068c77c0d353552bec47253526f1dc1796871d1d818c21c1409e163a7f760773b1ab7541037d52756c3484785caa837e54b30d0880659c042decb
• Download URL:
  https://stacks.cdc.gov/view/cdc/186784/cdc_186784_DS1.pdf
• File Type:
  [PDF - 336.77 KB ]