Oral and Dermal Toxicity of Organophosphate Pesticides in the Domestic Pigeon (Columba livia)

Details

• Personal Author:
  Fry DM ; Henderson JD ; Seiber JN ; Wilson BW ; Yamamoto JT
• Description:
  Low levels of blood and brain cholinesterases (ChE) are widely accepted biomarkers of exposure to anticholinergic pesticides, especially organophosphate (OP) esters (Ludke et al., 1975; Fleming, 1981; Wilson et al., 1992). The relatively rapid recovery of ChE levels due to hydrolysis of OP pesticide-ChE complexes and synthesis of plasma ChEs often lead investigators to infer that the exposures were both acute and recent. During the course of studying exposures of raptors to dormant sprays in orchards (Hooper et al., 1989; Wilson et al., 1991; Fry et al., 1993; Seiber et al., 1993), we undertook research on pigeons (Columba livia) as surrogates for wild birds such as Red-tailed Hawks (Buteo jamaicensis). This report presents oral and dermal toxicities of commonly used orchard sprays, ethyl parathion, diazinon and methidathion, to this readily available experimental animal. [Description provided by NIOSH]
• Subjects:
  Animals Chemical Warfare Agents Insecticides Nervous System Nervous System Disorders Occupational Exposure Occupational Health Organophosphates Safety
• Keywords:
  Acute-exposure Brain-function Central-nervous-system-disorders Chemical-warfare-agents Exposure-levels Organo-phosphorus-compounds Organo-phosphorus-pesticides Pesticides
• ISSN:
  0007-4861
• Document Type:
  Text
• Funding:
  Cooperative Agreement
• Genre:
  Journal Article
• Place as Subject:
  California ; OSHA Region 9
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  52
• Issue:
  5
• NIOSHTIC Number:
  nn:20032826
• Citation:
  Bull Environ Contam Toxicol 1994 May; 52(5):633-640
• Contact Point Address:
  J. D. Henderson, Department of Avian Sciences, University of California, Davis, 95616 California, USA
• CAS Registry Number:
  Coumaphos (CAS RN 56-72-4) ; Diazinon (CAS RN 333-41-5)
• Federal Fiscal Year:
  1994
• Performing Organization:
  University of California - Davis
• Peer Reviewed:
  True
• Start Date:
  19900930
• Source Full Name:
  Bulletin of Environmental Contamination and Toxicology
• End Date:
  20020929
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:491fe2377c2d5cde2622799e86b4a1c111b3471e793d598ba9e77a401b68469cd1e160e7dd85d7fd85d819594218f384d2c929de82dc0af582256ababbf6fc38
• Download URL:
  https://stacks.cdc.gov/view/cdc/186651/cdc_186651_DS1.pdf
• File Type:
  [PDF - 388.46 KB ]