Correlation Between the Content of Intermediate Chain-Length Fatty Acids and Copper in the Milk of Fulani Women

Details

• Personal Author:
  Glew RH ; Huang YS ; Millson M ; Shores JT ; VanderJagt DJ
• Description:
  Intermediate chain-length fatty acids (C10-C14) in human milk triglycerides provide an easily absorbable fuel that provide a significant amount of the energy needed for growth during the first few months of life. The C10-C14 fatty acid and trace mineral content of human milk is variable. In this report we examined the relationship between the content of calcium, copper, magnesium, manganese, phosphorus, and zinc, and the weight percentage of C10-C14 fatty acids in milk from 33 Fulani women in northern Nigeria between 2 and 24 weeks post-gestation. The milk from these women contained proportions of C10-C14 fatty acids that were comparable to those reported for other populations around the world, as were the concentrations of Ca, Cu, Mg, Mn, Zn and P. Significant correlations were observed between the milk content of Cu and the wt% of C10 (P=0. 005, r=0.475), C12 (P=0.001, r=0.539), C14 (P=0.44, r=0.352) and the total intermediate chain-length fatty acids (P=0.008, r=0.450). No correlations were observed between these fatty acids and any of the other five minerals. We speculate that the relationship between Cu and fatty acids could be related to a requirement for Cu by an enzyme required for C10-C14 fatty acid biosynthesis (e.g. decanoyl deacylase) in mammary tissue, or to some unique Cu binding properties of the intermediate chain length fatty acids. [Description provided by NIOSH]
• Subjects:
  Energy Metabolism Growth Occupational Health Safety Women
• Keywords:
  Energy-metabolism Fat-metabolism Growth-factors Human-factors-engineering Humans Physiological-factors
• ISSN:
  0952-3278
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  New Mexico ; Ohio ; OSHA Region 5 ; OSHA Region 6
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DART - Division of Applied Research and Technology
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  203-207
• Volume:
  63
• Issue:
  4
• NIOSHTIC Number:
  nn:20032335
• Citation:
  Prostaglandins, Leukot Essent Fat Acids 2000 Oct; 63(4):203-207
• Contact Point Address:
  Robert H. Glew, PhD, Department of Biochemistry and Molecular Biology, School of Medicine, University of New Mexico School of Medicine, Albuquerque, New Mexico 87131
• Email:
  rglew@salud.unm.edu
• Federal Fiscal Year:
  2001
• Peer Reviewed:
  True
• Source Full Name:
  Prostaglandins, Leukotrienes, and Essential Fatty Acids
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:6a8580ae3d8aaa41434862e3f0c2ada723c6d5898402def068bf02df31f76a0f88c5b64bba9e45b7c303ab2ae4df9c28fcb13ed7dac10eac22fe275cefd9bbc1
• Download URL:
  https://stacks.cdc.gov/view/cdc/186353/cdc_186353_DS1.pdf
• File Type:
  [PDF - 111.08 KB ]