Cancer risk of asbestos exposure.

Details

• Personal Author:
  Selikoff IJ
• Description:
  Aspects pertaining to the risk of cancer from asbestos (1332214) exposure are discussed. Studies are reviewed concerning the carcinogenicity of asbestos, current perspectives on the incidence and course of asbestos related diseases, and public health considerations in the control of asbestos related diseases. Comparatively few studies of asbestos associated diseases were undertaken before the 1920s. Shortly thereafter, it was discovered that many of the asbestos related diseases had a 20 year latency period. Diseases associated with and symptoms related to asbestos exposure include pleural abnormalities, lung cancer, pleural mesothelioma, peritoneal mesothelioma, and gastrointestinal cancer. Amosite (12172735), anthophyllite (16829439), chrysotile (12001295), and crocidolite (12001284) have all been known to produce neoplasms and other disorders. Research from the 1960s to current times has found many answers regarding dose/disease response, dose/induction period, period of clinical latency, multiple factor interactions, family contact diseases, and neighborhood exposure. Current research interests include the effects of low concentration exposures; asbestos contamination of public water supplies; maintenance, repair, demolition, and disposal of asbestos materials; and the identification of high risk groups. [Description provided by NIOSH]
• Subjects:
  Asbestos Carcinogens Dust Inorganic Chemicals Neoplasms Nervous System Occupational Health Risk Assessment Risk Factors Safety
• Keywords:
  Asbestos-fibers Biological-effects Cancer-rate Carcinogenesis Clinical-symptoms Dose-response Dust-exposure Exposure-levels Medical-research Neoplastic-agents Risk-factors

  More +
• ISBN:
  9780879691196
• Publisher:
  Cold Spring Harbor Laboratory
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Proceedings
• Place as Subject:
  New York ; OSHA Region 2
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  4
• NIOSHTIC Number:
  nn:00158186
• Citation:
  Origins of human cancer. Book C. Human risk assessment. Hiatt HH, Watson JD, Winsten JA, eds. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory, 1977 Jan; 4:1765-1784
• CAS Registry Number:
  Amosite asbestos (CAS RN 12172-73-5) ; Asbestos (CAS RN 1332-21-4) ; Chrysotile (CAS RN 12001-29-5) ; Crocidolite asbestos (CAS RN 12001-28-4) ; Magnesio-anthophyllite (CAS RN 16829-43-9)
• Editor(s):
  Hiatt HH; Watson JD; Winsten JA
• Federal Fiscal Year:
  1977
• Peer Reviewed:
  False
• Start Date:
  19700501
• Source Full Name:
  Origins of human cancer. Book C. Human risk assessment
• End Date:
  19790630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:d63fa5819c7fc10d3bf214c3cc93b03f710b0054008d91035c211dcdb765485feba89475dd10eb85936bb0c4e54c9ba68a8a9450eb955df2fd36fc28697a74cc
• Download URL:
  https://stacks.cdc.gov/view/cdc/184955/cdc_184955_DS1.pdf
• File Type:
  [PDF - 7.68 MB ]