Environmental levels and urine content of workers exposed to azo dyes.

Details

• Personal Author:
  Boeniger, Mark F. ; Bowman M ; Lowry, Larry K. ; Nony CR ; Tolos, William P.
• Description:
  Worker exposure to azo dyes derived from benzidine (92875) and urinary excretion of benzidine and its metabolites were studied. Environmental exposures to benzidine were determined from personal and bulk air samples, and work practices were observed in two textile dyeing and finishing facilities, a leather tanning facility, a specialty paper company, and two benzidine dye manufacturing facilities. Urine samples from 38 employees potentially exposed to benzidine derived dyes were analyzed. Urine of 12 of the 38 workers monitored contained benzidine or monoacetylbenzidine (3366618) in quantities ranged from 1 part per billion (ppb) to 112ppb benzidine and up to 590ppb monoacetylbenzidine. Total airborne particulate concentrations of benzidine above 3 to 5 milligrams per cubic meter (mg/CuM) often resulted in the detection of benzidine, its metabolites, or elevated nonspecific aromatic amines in the urine of exposed workers. Exposure to airborne particulates less than 3mg/CuM were associated less often with aromatic amines in the urine. Full shift airborne exposures as low as 1.1mg/CuM resulted in considerable urinary benzidine. The author concludes that it is unlikely that benzidine derived dyes can be used in a sufficiently controlled and safe manner. [Description provided by NIOSH]
• Subjects:
  Coloring Agents Energy Metabolism Occupational Health Safety Surveys And Questionnaires
• Keywords:
  Coloring-materials Dyes Health-surveys Industrial-hygiene Metabolites
• Publisher:
  NCI; EPA; NIOSH
• Document Type:
  Text
• Genre:
  Proceedings
• Place as Subject:
  District of Columbia ; Maryland ; OSHA Region 3
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• NIOSHTIC Number:
  nn:00123081
• Citation:
  Proceedings of the first NCI/EPA/NIOSH collaborative workshop: progress on joint environmental and occupational cancer studies, May 6-8, 1980, Rockville, Maryland. Kraybill HF, Blackwood IC, Freas NB, eds. Washington, DC: National Cancer Institute, Environmental Protection Agency, National Institute for Occupational Safety and Health, 1980 May; :775-797
• CAS Registry Number:
  4,4'-Diaminodiphenyl (CAS RN 92-87-5) ; Acetylbenzidine (CAS RN 3366-61-8)
• Editor(s):
  Kraybill HF; Blackwood IC; Freas NB
• Federal Fiscal Year:
  1980
• Peer Reviewed:
  False
• Source Full Name:
  Proceedings of the first NCI/EPA/NIOSH collaborative workshop: progress on joint environmental and occupational cancer studies, May 6-8, 1980, Rockville, Maryland
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:447446a3c08ef9467898bc4dfc2769fa604c42d4750f2c2b237a45136094d19d834f14e91cf26cde02308ecd63d2456b272432e32c0b31ee673b41b45715839b
• Download URL:
  https://stacks.cdc.gov/view/cdc/184551/cdc_184551_DS1.pdf
• File Type:
  [PDF - 615.89 KB ]