Liver function among neoprene production workers.

Details

• Personal Author:
  Gilmer PR Jr. ; Schoen I ; Ward JB Jr. ; Whorton EB
• Description:
  Liver function was tested in neoprene (9010984) production workers. Blood samples from 81 workers at the Denka Chemical Company (SIC- 2822) in Houston, Texas were analyzed for various proteins and enzymes related to liver function. Information also was obtained on other medical problems of the workers. Increases in serum glutamate oxaloacetate transaminase, serum glutamate pyruvate transaminase, gamma glutamyl transpeptidase, and alkaline phosphatase were significantly related to reported alcohol consumption. This precluded evaluation of exposure related effects. However, some trend toward increased values was found among workers in high exposure areas. Other exposure effects included reproductive difficulties, respiratory problems, cardiac disorders, and central nervous system symptoms. The authors suggest that chemical exposures related to neoprene production cause liver function disturbances, and that exposed workers who drink alcohol may be at an even greater risk. They recommended a more comprehensive evaluation of these workers and of the health effects of neoprene exposure. [Description provided by NIOSH]
• Subjects:
  Digestive System Liver Manufacturing And Industrial Facilities Occupational Health Safety Surveys And Questionnaires
• Keywords:
  Chemical-industry-workers Health-surveys Liver-disorders Liver-function Medical-examinations Medical-screening Occupational-medicine
• Document Type:
  Text
• Genre:
  Report
• Place as Subject:
  OSHA Region 6 ; Texas
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-54
• NIOSHTIC Number:
  nn:00118735
• NTIS Accession Number:
  PB82-231044
• Citation:
  University of Texas Medical Branch, Galveston,Texas, 1981 Oct; :1-54
• CAS Registry Number:
  Polychloroprene (CAS RN 9010-98-4)
• Federal Fiscal Year:
  1982
• Peer Reviewed:
  False
• NAICS and SIC Codes:
  2822 - Synthetic rubber - (SIC)
• Source Full Name:
  University of Texas Medical Branch, Galveston,Texas
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:9b4361f447ab696d29bb17161ea2d5178d219d2685aabdd19dc7d7f1c48707ed8bdcbcdab9ded4aa26c27834708db834fe36ff91ff5e49cf0bdc4cc2e6532ebf
• Download URL:
  https://stacks.cdc.gov/view/cdc/184492/cdc_184492_DS1.pdf
• File Type:
  [PDF - 1.59 MB ]