Chlorobenzilate residues in urine.

Details

• Personal Author:
  Brady SS ; Enos HF ; Levy KA
• Description:
  Absorption of pesticides was investigated by analyzing the excretion of the parent compound or appropriate metabolites in urine samples to develop an analytical method for monitoring human exposure to chlorobenzilate (510156). Urine was collected from treated rats and citrus grove workers for chromatographic analysis. The 4,4'-dichlorobenzophenone (90982) (DBP) oxidized metabolite averaged less than 0.01 parts per million (ppm) in predose rats and non-exposed human urine samples. DBP residues were calculated back to the ppm chlorobenzilate by multiplying DBP by 1.29 and dividing by the milligram urine equivalents injected. The 4,4'-Dichlorobenzilic acid fortified urines (at 0.05ppm) from non-exposed humans that were analyzed with citrus worker sample, resulted in recoveries that averaged 97 percent. [Description provided by NIOSH]
• Subjects:
  Absorptiometry, Photon Agriculture Biochemistry Blood Energy Metabolism Hematologic Tests Insecticides Occupational Health Safety Urine
• Keywords:
  Absorptiometry Agricultural-workers Analytical-methods Biochemical-effects Blood-chemistry Body-retention Elimination Metabolic-effects Pesticides-and-agricultural-chemicals Urinalysis
• ISSN:
  0007-4861
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  Florida ; OSHA Region 4
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  24
• Issue:
  5
• NIOSHTIC Number:
  nn:00096186
• Citation:
  Bull Environ Contam Toxicol 1980 May; 24(5):813-815
• CAS Registry Number:
  4,4′-Dichlorobenzophenone (CAS RN 90-98-2) ; Chlorobenzilate (CAS RN 510-15-6)
• Federal Fiscal Year:
  1980
• NORA Priority Area:
  Grants Other
• Performing Organization:
  University of Miami, Miami, Florida
• Peer Reviewed:
  True
• Start Date:
  19770701
• Source Full Name:
  Bulletin of Environmental Contamination and Toxicology
• End Date:
  19810630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:2d0261f4842dd70d80424dbea4f6a2dda6b694886c3afe8510115b3c2b88c57388d37a8deec5c1f8e99644a41ef63f033a112162b28fcbdd17f8657286f3a57d
• Download URL:
  https://stacks.cdc.gov/view/cdc/184351/cdc_184351_DS1.pdf
• File Type:
  [PDF - 156.49 KB ]