Propanil-chloracne and methomyl toxicity in workers of a pesticide manufacturing plant.

Details

• Personal Author:
  Baker EL Jr. ; Kimbrough RD ; Morse DL ; Wisseman CL III
• Description:
  A questionnaire, medical records, and blood and urine samples were used to survey instances of occupationally related hospitalization among 102 workers at a pesticide facility in rural Arkansas that manufactured 1-lambda-methylthioethylideneamino methyl carbamate (16752775) (methomyl) and 3,4-dichloropropionanilide (709988) (propanil), a herbicide made from 3,4-dichloraniline (95761). Packaging workers had the highest rate of illness and hospitalization, and experienced blurred vision or pupillary constriction. Production workers exposed to dichloroaniline and propanil had the highest incidence of chloracne. Rabbit ear tests verified the chloracnegenic potential of propanil and 3,4- dichloroaniline. The authors conclude that a hazard exists in the manufacture and formulation of pesticides and herbicides, and report that industrial hygiene improvements in the packaging area have decreased the illness rate at the pesticide facility surveyed. [Description provided by NIOSH]
• Subjects:
  Epidemiology Hazardous Substances Insecticides Manufacturing And Industrial Facilities Occupational Health Safety
• Keywords:
  Biostatistics Chemical-industry Chemical-workers Data-collection Medical-screening NIOSH-Author Pest-control Physiological-effects Toxic-substances
• ISSN:
  0009-9309
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Georgia ; Massachusetts ; New York ; North Carolina ; Ohio ; OSHA Region 1 ; OSHA Region 2 ; OSHA Region 4 ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  13-21
• Volume:
  15
• Issue:
  1
• NIOSHTIC Number:
  nn:00091913
• Citation:
  Clin Toxicol 1979 Jul; 15(1):13-21
• CAS Registry Number:
  3,4-Dichloroaniline (CAS RN 95-76-1) ; Methomyl (CAS RN 16752-77-5) ; Propanil (CAS RN 709-98-8)
• Federal Fiscal Year:
  1979
• Peer Reviewed:
  True
• Source Full Name:
  Clinical Toxicology
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:111ccf6c0556be09abdba8b743ff6492c31e26acc1b8c1b3c46b0995c972730c31ca141207bf3391c606483b1e607dbbcca0d244a692e3821c64b8881a4e560c
• Download URL:
  https://stacks.cdc.gov/view/cdc/184285/cdc_184285_DS1.pdf
• File Type:
  [PDF - 653.24 KB ]