Lung volumes, mechanics, and single-breath diffusing capacity in anesthetized cats.

Details

• Personal Author:
  Frank R ; Watanabe S
• Description:
  We measured lung weight, lung volumes, pulmonary mechanics, and carbon monoxide transfer (DLCO, single-breath method) in healthy cats (3.3 +/- 0.4 kg) that were anesthetized, paralyzed, and mechanically ventilated through a tracheal cannula. Compared with Stahl's predicted values which were based on regression analyses of data collected from several species, our cats had larger and more compliant lungs in relation to body weight, higher DLCO per unit body weight, and similar DLCO/TLC (size independent constant). Compared with Robinson et al.'s values derived entirely from studies on dogs, our cats had significantly smaller lung volumes and DLCO per unit body weight, DLCO/TLC and similar ratios of CL/FRC. Several factors appear to contribute to the functional variations among mammalian species: differences in the relation of lung to body weight, differences in the relation of chest wall compliance to lung compliance, and differences in the fundamental structure and design of the respiratory systems. Differences in methodology are acknowledged to be an additional factor. [Description provided by NIOSH]
• Subjects:
  Biomechanical Phenomena Occupational Health Respiratory System Safety
• Keywords:
  Biomechanics JAPYAA Lung-function-tests NIOSH-Grant NIOSH-Publication Physiological-measurements Respiratory-system
• ISSN:
  8750-7587
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 10 ; Washington
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  38
• Issue:
  6
• NIOSHTIC Number:
  nn:00048135
• Citation:
  J Appl Physiol 1975 Jun; 38(6):1148-1152
• Contact Point Address:
  Preventive Medicine University of Washington Dept of Preventive Medicine Seattle, Wash 98105
• Federal Fiscal Year:
  1975
• NORA Priority Area:
  Pulmonary System Disorders
• Performing Organization:
  University of Washington, Seattle, Washington
• Peer Reviewed:
  True
• Start Date:
  19701001
• Source Full Name:
  Journal of Applied Physiology
• End Date:
  19770331
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:6210e1591e79255b01833826989ba3439c640e5bc722aaab9b4981f2eeb81edb1686e84defcb6e458034557f5a4bdfc50b87803356359f8351bc5a3146a52588
• Download URL:
  https://stacks.cdc.gov/view/cdc/184044/cdc_184044_DS1.pdf
• File Type:
  [PDF - 1.06 MB ]