Changes in pulmonary function in workers exposed to vinyl chloride and polyvinyl chloride.

Details

• Personal Author:
  Chuang M ; Miller, Aubrey K. ; Selikoff IJ ; Teirstein AS ; Warshaw R
• Description:
  Spirometry and maximum expiratory flow-volume curves are obtained in 348 workers in a vinyl-chloride (75014) polymerization plant to determine whether occupational exposure to vinyl-chloride gas and polyvinyl-chloride (9002862) dust is associated with changes in pulmonary function. The major finding is diminution in air flow in 200 workers (57.5 per cent), an abnormality correlated with age and duration of exposure. A relationship with smoking is noted only in younger workers with exposures of less than 10 years. When age exceeds 40 years or exposure 20 years, prevalence of this impairment is similar in smokers and nonsmokers, suggesting that occupational or other environmental factors are operative. [Description provided by NIOSH]
• Subjects:
  Epidemiology Hazardous Substances Hydrocarbons Occupational Health Plastics Polymers Respiratory Tract Diseases Safety
• Keywords:
  Chlorinated-hydrocarbons NIOSH-Grant NIOSH-Publication Plastics-industry Pulmonary-system-disorders Smoking-habits Toxic-gases
• ISSN:
  0077-8923
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  New York ; OSHA Region 2
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  42-52
• Volume:
  246
• NIOSHTIC Number:
  nn:00036470
• Citation:
  Ann NY Acad Sci 1975 Jan; 246:42-52
• Contact Point Address:
  Community Medicine Mount Sinai School of Medicine Fifth Avenue and 100 Street New York, N Y 10029
• CAS Registry Number:
  Poly(vinyl chloride) (CAS RN 9002-86-2) ; Vinyl chloride (CAS RN 75-01-4)
• Federal Fiscal Year:
  1975
• NORA Priority Area:
  Pulmonary System Disorders
• Performing Organization:
  Mount Sinai School of Medicine, New York, New York
• Peer Reviewed:
  True
• Start Date:
  19700501
• Source Full Name:
  Annals of the New York Academy of Sciences
• End Date:
  19790630
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:af03c7d13011579a3a22dc31a9109d45313f2dd8a3e9e6d58025ac04c3907a93a8bfe106304058e708966bc7afc6cbf32616540f2bebacab2b6532fc1f3fcdb0
• Download URL:
  https://stacks.cdc.gov/view/cdc/183963/cdc_183963_DS1.pdf
• File Type:
  [PDF - 592.63 KB ]