Two patterns for bronchial damage from inhaled materials.

Details

• Personal Author:
  Halprin GM ; Hudson AR ; Kilburn KH ; McKenzie WN ; Merchant, James A.
• Description:
  Morphology of distal airway cells, and the leukocyte recruitment phenomenon are studied after exposure of hamsters or guinea-pigs to dust or aerosol. Bronchial damage from inhaled materials may consist of epithelial cell vacuolization, nuclear extrusion and cellular extrusion, or polymorphonuclear leukocyte recruitment. Nonparticulate materials given as aerosols, particularly gossypol and paraquat (1910425), are deposited out to peripheral airways as judged by cell damage, while particles recruit leukocytes without producing ultrastructural damage to cells. [Description provided by NIOSH]
• Subjects:
  Air Pollutants, Occupational Air Pollution, Indoor Byssinosis Cytology Herbicides Occupational Health Particulate Matter Respiratory Tract Diseases Safety
• Keywords:
  Air-contamination Airborne-particulates Cytopathology NIOSH-Grant NIOSH-Publication Respiratory-system-disorders
• ISSN:
  0012-3692
• Document Type:
  Text
• Funding:
  Grant
• Genre:
  Journal Article
• Place as Subject:
  North Carolina ; OSHA Region 4
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  61-62
• Volume:
  65
• Issue:
  4
• NIOSHTIC Number:
  nn:00028116
• Citation:
  Chest 1974 Apr; 65(4):61-62
• Contact Point Address:
  Medicine Duke University ED Ctr Durham, N C 27706
• CAS Registry Number:
  Methyl viologen (CAS RN 1910-42-5)
• Federal Fiscal Year:
  1974
• NORA Priority Area:
  Pulmonary System Disorders
• Performing Organization:
  Duke University, Durham, North Carolina
• Peer Reviewed:
  True
• Start Date:
  19710201
• Source Full Name:
  Chest
• End Date:
  19740131
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:98280d0124a420e218db161e79e8fa5f1605262fc976b76dba3754997936bdc431769918263f41de36d3e872ae7c03aa6b8f7b30f104d3f7d754edcc8a54b1ec
• Download URL:
  https://stacks.cdc.gov/view/cdc/183924/cdc_183924_DS1.pdf
• File Type:
  [PDF - 250.21 KB ]