Serum trypsin inhibitor capacity and purulent sputum.

Details

• Personal Author:
  Kibelstis JA ; Resnick H
• Description:
  Abnormal serum activities of alpha(1)-antitrypsin have been found in association with a variety of pathologic conditions. It has also been shown that the proteinase inhibitor is genetically determined, and 3 values of trypsin inhibitor capacity (TIC: milligrams of trypsin (9002077) inhibited per milliliter of serum) have been recognized. The purpose of this study was to determine whether the presence of a purulent sputum had any significant effect on alpha(1)- antitrypsin values. In 16 patients, the products of purulent sputum, without overt signs of more severe infection, were associated with an increase in serum trypsin inhibitor capacity. [Description provided by NIOSH]
• Subjects:
  Enzyme Inhibitors Epidemiology Genetics Occupational Health Pathology Respiratory Tract Diseases Safety
• Keywords:
  Enzymatic-inhibition Excretions NIOSH-Author Respiratory-system-disorders Screening Serology
• ISSN:
  0003-0805
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  ALFORD - Appalachian Laboratory for Occupational Respiratory Disease
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Volume:
  106
• Issue:
  5
• NIOSHTIC Number:
  nn:00020484
• Citation:
  Am Rev Respir Dis 1972 Oct; 106(5):772-773
• CAS Registry Number:
  Trypsin (CAS RN 9002-07-7)
• Federal Fiscal Year:
  1973
• NORA Priority Area:
  Pulmonary System Disorders
• Peer Reviewed:
  True
• Source Full Name:
  American Review of Respiratory Disease
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:e54325eb0968fa09c019205f32938977f28b6972793e0562bdda1df74af905ec5ab7f8a91dccf796b7a6d2d3240ca9e1b0ec4c27dfce1f71c137d5eff8237c44
• Download URL:
  https://stacks.cdc.gov/view/cdc/183833/cdc_183833_DS1.pdf
• File Type:
  [PDF - 120.25 KB ]