Reproductive Abnormalities in Male Chemical Workers – Kentucky

Details

• Journal Article:
  Morbidity and Mortality Weekly Report (MMWR)
• Corporate Authors:
  National Institute for Occupational Safety and Health
• Description:
  The National Institute for Occupational Safety and Health (NIOSH) found, in a recent investigation at a chemical plant in Kentucky, that workers exposed to toluenediamine (TDA) and dinitrotoluene (DNT) in the production of TDA had lowered sperm counts. This evaluation was requested by workers at a chemical plant in Brandenburg, Kentucky, following the discovery of abnormal sperm morphology (specifically, the presence of elevated numbers of tapering forms) in a worker in the TDA unit. This worker had sought clinical evaluation because of his concern about the relationship between his chemical exposures and his wife's recent miscarriages. To evaluate this clinical finding, NlOSH investigators administered medical questionnaires concerning reproductive history and workplace exposures; conducted physical examinations of workers, concentrating on reproductive and endocrine systems; obtained blood specimens for renal and liver function tests; and examined semen specimens for ejaculate volume, sperm count, and sperm morphology. [Description provided by NIOSH]
• Subjects:
  Diagnosis Hazardous Substances Hematologic Tests Manufacturing And Industrial Facilities Men Occupational Exposure Occupational Health Safety Surveys And Questionnaires Urogenital Diseases Urogenital System

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• Keywords:
  Blood Samples Chemical Factory Workers Chemical Hazards Chemical Industry Workers Chemical Manufacturing Industry Clinical Diagnosis Clinical Tests Dinitrotoluene Employee Exposure Medical Surveys Morphology Occupational Exposure Physical Examination Questionnaires Reproductive Effects Reproductive Hazards Reproductive System Disorders Toluenediamine

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• Series:
  Weekly Report: Morbidity and Mortality Weekly Report (MMWR)
• ISSN:
  0149-2195 (print) ; 1545-861X (digital)
• Publisher:
  Centers for Disease Control and Prevention (CDC) (U.S.)
• Document Type:
  Text
• Genre:
  Journal Article
• Place as Subject:
  Kentucky ; OSHA Region 4
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  4 pdf pages
• Volume:
  30
• Issue:
  17
• NIOSHTIC Number:
  nn:20055435
• Citation:
  MMWR 1981 May; 30(17):199-200,205
• CAS Registry Number:
  2,4-Diaminotoluene (CAS RN 95-80-7) ; 2,4-Dinitrotoluene (CAS RN 121-14-2) ; Dinitrotoluene (CAS RN 25321-14-6)
• Federal Fiscal Year:
  1981
• Peer Reviewed:
  False
• Collection(s):
  Morbidity and Mortality Weekly Report (MMWR) National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:ede5f776d59f5d37981a8be2c0242f4cd9336c92fada4c42d24fbaf96d54b15e7529b2f5ff4ab1a39db29e534cdaf88d5fdc3589bc25af8add454826db9d89d0
• Download URL:
  https://stacks.cdc.gov/view/cdc/183278/cdc_183278_DS1.pdf
• File Type:
  [PDF - 395.45 KB ]