Serum IgE, levels wheezing and lung function in a normal urban population in Bombay, India.

Details

• Personal Author:
  Bhosale AM ; Chowgule RV ; Gupta PC ; Lewis, Dick ; Shetye VM ; Vallyathan V
• Description:
  There is great concern about the respiratory hazards associated with urban city dwelling. Relatively little is known about the long-term health effects of urban living in normal young adults. We investigated the prevalence of respiratory symptoms and serum IgE levels in 270 normal individuals between 20-40 of age with no self-reported respiratory symptoms of asthma. The subjects were drawn. from a two-stage random sample of 457 life-time urban dwellers in Bombay. lgE levels were significantly elevated in 33% of subjects (>525 KU IgE/L). Individuals with increased levels of IgE (15%) admitted to having wheezed at least once in the previous year, compared to 5% with normal IgE levels. On the other hand 30% of subjects with increased IgE levels had at least one positive skin prick test compared to 18% with normal IgE levels. All subjects in the study group had a normal spirometry. We conclude that there is a high prevalence of atopy in asymptomatic subjects in the population exposed to urban air pollutants we studied.
• Subjects:
  Accidents, Occupational Air Pollution Cotton Fiber Dust Gossypium Industrial Waste Occupational Health Particulate Matter Respiratory System Respiratory Tract Diseases Safety Ventilation

  More +
• Keywords:
  Air Pollution Asthma Health Effects Lung Function Respiratory Function
• Publisher:
  National Institute for Occupational Safety and Health
• Document Type:
  Text
• Genre:
  Abstract
• Place as Subject:
  OSHA Region 3 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  HELD - Health Effects Laboratory Division
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1
• NIOSHTIC Number:
  nn:20057249
• Citation:
  Occupational asthma: in and out of the workplace conference, April 30 - May 2, 1998, Morgantown, West Virginia. Morgantown, WV: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, 1998 Apr; :1
• Federal Fiscal Year:
  1998
• Peer Reviewed:
  False
• Source Full Name:
  Occupational asthma: in and out of the workplace conference, April 30 - May 2, 1998, Morgantown, West Virginia
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:8515ae4f8f08e27863ff6c3fc917d5c6272f77817385418203a377066a7abd540a259818c7a95d454d54211cd8529b754e620b6348f8df2198d8fab6535ad331
• Download URL:
  https://stacks.cdc.gov/view/cdc/181805/cdc_181805_DS1.pdf
• File Type:
  [PDF - 428.23 KB ]