Lead skin absorption and the effects of cleaning procedure with detergents.

Details

• Personal Author:
  Adami G ; Boeniger, Mark F. ; Cozzi F ; Damian A ; Larese Filon F ; Maina G
• Description:
  Skin contamination by dusts containing lead and other toxic metals is not generally regarded by many as posing significant risks for absorption and toxic effects. Limited experimental studies suggest that under physiologically relevant conditions metal dusts may ionize, which can increase risks of percutaneous absorption of toxic metals (Stauber 1994, Hostynek 2003, Larese 2004). It is known that polar organic compounds and some metals can appreciably be absorbed through damaged skin but this has not been studied in regards to lead particulate compounds (e.g., PbO, PbO2. etc). Previous in-vivo experiments with inorganic lead compounds indicate absorbtion through the skin (Stauber 1994) but there was previously no information on the effect on absorption of decontamination agents. The aim of our study was to investigate the skin absorption of PbO, the effect of a rapid skin decontamination with two different detergents and the comparative absorption in normal or abraded skin.
• Subjects:
  Accidents, Occupational Chromatography Environmental Exposure Environmental Pollution Hazardous Substances Occupational Exposure Occupational Health Safety
• Keywords:
  Absorption-rates Aerosol-particles Aerosols Decontamination Detergents Dusts Lead-absorption Lead-dust Lead-poisoning Occupational-hazards Occupational-health Particulate-dust Particulates Skin-absorption Skin-exposure Skin-irritants

  More +
• Publisher:
  National Institute for Occupational Safety and Health
• Document Type:
  Text
• Genre:
  Conference/Symposia Proceedings
• Place as Subject:
  Ohio ; OSHA Region 3 ; OSHA Region 5 ; West Virginia
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-3
• NIOSHTIC Number:
  nn:20027243
• Citation:
  Occupational and Environmental Exposures of Skin to Chemicals, June 12-15, 2005, Stockholm, Sweden. Morgantown, WV: National Institute for Occupational Safety and Health, 2005 Jun; :1-3
• CAS Registry Number:
  Lead (CAS RN 7439-92-1)
• Federal Fiscal Year:
  2005
• Peer Reviewed:
  False
• Source Full Name:
  Occupational and Environmental Exposures of Skin to Chemicals, June 12-15, 2005, Stockholm, Sweden
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:d3b9ffa48365856d210ca7cc762341eaf8af6f70014a64f8cf5afe4dce1d0d4fce433235572b4353cca15afa5fd543ffb1aa5ef4effd6d7ee2977eb3abd5cae5
• Download URL:
  https://stacks.cdc.gov/view/cdc/181312/cdc_181312_DS1.pdf
• File Type:
  [PDF - 626.83 KB ]