NIOSH testimony on risk estimates from the Cadmium Cohort Study by L. Stayner, February 7, 1992.

Details

• Corporate Authors:
  National Institute for Occupational Safety and Health
• Description:
  This testimony includes a table summarizing the risk estimates from fitting the multistage model to a specific cadmium (7440439) cohort study. The risk estimates from fitting the multistage model to the cadmium study were intermediate between estimates derived from fitting the Cox and Poisson regression models. NIOSH further notes that the risk estimates from the Cox and Poisson models are about 50% higher than the estimates in the risk assessment report submitted earlier by NIOSH. The lifetime risk was calculated over the entire life span rather than the median life span. Lung cancer rates were used rather than respiratory cancer rates. NIOSH assumed a five stage model for the analysis, as this is the number of stages generally observed in other multistage analyses of lung cancer. The model was fit by varying the stage affected by cadmium exposure and the model fit best when NIOSH assumed that cadmium affected the third stage.
• Subjects:
  Accidents, Occupational Biochemistry Growth Hazardous Substances Occupational Health Safety Thiophenes Urogenital System
• Keywords:
  Cancer-rates Epidemiology Mortality-data NIOSH-Author NIOSH-Testimony Occupational-exposure Risk-analysis Stayner-L
• Document Type:
  Text
• Genre:
  Testimony
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSDTT - Division of Standards Development and Technology Transfer
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-8
• NIOSHTIC Number:
  nn:00228292
• Citation:
  NIOSH 1992 Feb; :1-8
• CAS Registry Number:
  Cadmium (CAS RN 7440-43-9)
• Federal Fiscal Year:
  1992
• Peer Reviewed:
  False
• Source Full Name:
  NIOSH, 8 pages, 4 references
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:4a0270d9958b5302aaaa5b3a9a237160d481c25e2a889b890774474afa7a229c73dd941c51581a69142d928bf64e98ebbe7c59b9bc05f4eca85a2aa452d24af5
• Download URL:
  https://stacks.cdc.gov/view/cdc/180936/cdc_180936_DS1.pdf
• File Type:
  [PDF - 1.09 MB ]