Industrial hygiene report, walk-through survey, Mallinckrodt Specialty Chemicals Company, Chesterfield, Missouri.

Details

• Personal Author:
  Alderfer R ; Boeniger, Mark F.
• Description:
  A walk through survey was conducted at the Mallinckrodt Specialty Chemicals Company (SIC-2833) located in Chesterfield, Missouri to assess the feasibility of conducting studies on the immunotoxic effects of chemicals at this facility. The opiate refining facility at the site had been in constant operation for about 100 years. Morphine (57272), codeine (76573), thebaine (115377), noscapine (128621) and papaverine (58742) were produced. A total of 66 chemical operators, 20 salaried personnel and additional support staff were involved in the production of the opiates. Nine full time safety and health professionals were employed by the company. Urine samples were collected at scheduled periodic medical examinations and tested for opiates. Ventilation controls appeared minimal, but surfaces were free of accumulated dust. Personnel records appeared to be inadequate for retrospective mortality or morbidity studies. Because of incomplete or inconsistent data collection at various sites, it was difficult to determine if the findings at this site were comparable to those at other facilities. The authors conclude that additional exposure information may be needed to determine the feasibility of conducting a study at this facility.
• Subjects:
  Accidents, Occupational Hospitals Laboratories Occupational Exposure Occupational Health Preceptorship Safety Ventilation
• Keywords:
  Field-Study Industrial-hygiene IWS-194-10 Narcotics; NIOSH-Author NIOSH-Survey Occupational-exposure Pharmaceutical-industry Region-7 Urinalysis
• Publisher:
  National Institute for Occupational Safety and Health
• Document Type:
  Text
• Genre:
  Field Studies ; Industry Wide
• Place as Subject:
  Missouri ; Ohio ; OSHA Region 5 ; OSHA Region 7
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-7
• NIOSHTIC Number:
  nn:00218690
• Citation:
  Cincinnati, OH: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, IWS 194-10, 1993 Jul; :1-7
• CAS Registry Number:
  Morphine (CAS RN 57-27-2) ; Codeine (CAS RN 76-57-3) ; Thebaine (CAS RN 115-37-7) ; Noscapine (CAS RN 128-62-1) ; Papaverine (CAS RN 58-74-2)
• Federal Fiscal Year:
  1993
• Peer Reviewed:
  False
• NAICS and SIC Codes:
  2833 - Medicinals and botanicals - (SIC)
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:20faa39a3f8abd6148700ababe568da495c5807bfb1e5f5d048bb4fe61048b697c69748d2fef241fb1a9e11d7a4079625a55a33b7d961011769079e6ffa53007
• Download URL:
  https://stacks.cdc.gov/view/cdc/180864/cdc_180864_DS1.pdf
• File Type:
  [PDF - 344.64 KB ]