Real time detection of biological aerosols.

Details

• Personal Author:
  Goode MT ; Mackay RA ; Sarver EW ; Sickenberger DW ; Stopa PJ ; Zulich AW
• Description:
  The development of small, lightweight, rugged instruments which can be introduced into field applications for detecting biological aerosols was discussed. In immunological based sensors, antibodies are bound to either optical or electrochemical transducers. Fluorescent dyes or chromogenic enzyme substrates may be used for the transduction of optical signals. With an electrochemical sensor, enzyme/substrate combinations which yield electrochemically active species may be used. The Light Addressable Potentiometric Sensor and the Bio-Chemical Detector were described. The CBMS system used Quadrapole Ion Storage technology and allowed bacterial identification to the level of genus. The authors conclude that the biospecificity approach needs a lot of up front work in the development of biological reagents while the other approach requires a significant amount of work in the development of appropriate spectral libraries. Both systems show great promise.
• Subjects:
  Accidents, Occupational Occupational Health Personal Protective Equipment Respiratory Protective Devices Safety
• Keywords:
  Aerosol-sampling Air-quality-monitoring Analytical-methods Biohazards Biological-material Chemical-analysis Electrochemical-analysis Environmental-contamination
• Document Type:
  Text
• Genre:
  Conference/Symposia Proceedings
• Place as Subject:
  Florida ; OSHA Region 4
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  793-795
• NIOSHTIC Number:
  nn:00210445
• Citation:
  NIOSH 1991 Feb; :793-795
• Federal Fiscal Year:
  1991
• Peer Reviewed:
  False
• Source Full Name:
  Field Screening Methods for Hazardous Wastes and Toxic Chemicals. Second International Symposium, February 12-14, 1991. Sponsored by U.S. EPA; U.S. DOE; U.S. Army Toxic and Hazardous Materials Agency; U.S. Army Chemical Research Development and Engineering Center; U.S.A.F.; Florida State Univ.; National Environmental Technology Applications Corp.; and NIOSH
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:ec6f151db6a7ec70b8152929b03cf6fc408ed1ad6bb1d3a1835058a8cb7d5ecdbbe758492f72c9ccef30643e085af29d9f701886979288dfc5d3e1fba0e6fb59
• Download URL:
  https://stacks.cdc.gov/view/cdc/180811/cdc_180811_DS1.pdf
• File Type:
  [PDF - 235.80 KB ]