Anaplasma phagocytophilum from Rodents and Sheep, China

Zhan, Lin; Cao, Wu-Chun; Jiang, Jia-Fu; Zhang, Xiao-Ai; Liu, Yun-Xi; Wu, Xiao-Ming; Zhang, Wen-Yi; Zhang, Pan-He; Bian, Chang-Ling; Dumler, J. Stephen; Yang, Hong; Zuo, Shu-Qing; Chu, Chen-Yi; Liu, Wei; Richardus, Jan H.; Habbema, J. Dik F.

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Anaplasma phagocytophilum from Rodents and Sheep, China

Published Date:

May 2010

Source:

Emerg Infect Dis. 16(5):764-768.

[PDF - 230.47 KB]

Details:

Personal Authors:

Zhan, Lin ; Cao, Wu-Chun ; Jiang, Jia-Fu ; Zhang, Xiao-Ai ; Liu, Yun-Xi ; ... More ▼

Keywords:

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Description:

To characterize the strains of Anaplasma phagocytophilum in wild and domestic animals in China, we isolated the organism from rodents and sheep in northeastern China. We isolated 3 strains (2 from rodents and 1 from sick sheep) through propagation in BALB/c mice and then cell culture in HL60 cells. The 3 isolates were identified by Wright-Giemsa staining, immunofluorescence, and electronic microscopy and were characterized by sequence analyses of the 16S rRNA gene, partial citrate synthase gene, major surface protein 4 gene, and heat shock protein gene. The multiple sequences of the 3 isolates were identical to each other but different from all known strains from other countries. The public health and veterinary relevance of the isolates deserves further investigation.

Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases

Supporting Files:

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