Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Zhan, Lin ; Cao, Wu-Chun ; Jiang, Jia-Fu ; Zhang, Xiao-Ai ; Liu, Yun-Xi ; ... More +
Zhan, Lin ; Cao, Wu-Chun ; Jiang, Jia-Fu ; Zhang, Xiao-Ai ; Liu, Yun-Xi ; Wu, Xiao-Ming ; Zhang, Wen-Yi ; Zhang, Pan-He ; Bian, Chang-Ling ; Dumler, J. Stephen ; Yang, Hong ; Zuo, Shu-Qing ; Chu, Chen-Yi ; Liu, Wei ; Richardus, Jan H. ; Habbema, J. Dik F. Less -
Description:
To characterize the strains of Anaplasma phagocytophilum in wild and domestic animals in China, we isolated the organism from rodents and sheep in northeastern China. We isolated 3 strains (2 from rodents and 1 from sick sheep) through propagation in BALB/c mice and then cell culture in HL60 cells. The 3 isolates were identified by Wright-Giemsa staining, immunofluorescence, and electronic microscopy and were characterized by sequence analyses of the 16S rRNA gene, partial citrate synthase gene, major surface protein 4 gene, and heat shock protein gene. The multiple sequences of the 3 isolates were identical to each other but different from all known strains from other countries. The public health and veterinary relevance of the isolates deserves further investigation.
Subjects:
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Animals Citrate (si)-Synthase Cricetinae DNA, Bacterial Ehrlichiosis Heat-Shock Proteins HL-60 Cells Humans Membrane Proteins Mice Mice, Inbred BALB C Molecular Sequence Data Phylogeny Research RNA, Ribosomal, 16S Rodent Diseases Sequence Analysis, DNA Sheep Sheep Diseases
Source:
Emerg Infect Dis. 16(5):764-768.
Document Type:
Journal Article
Place as Subject:
China
Location:
Asia
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
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urn:sha256:56d52992e8eb0cecacd23ff6209a1a9ab2f30afc896f5cd60a0b544bb2231a06
Download URL:
https://stacks.cdc.gov/view/cdc/18074/cdc_18074_DS1.pdf
File Type:

Supporting Files

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