Muscularization of pulmonary arteries in coal workers pneumoconiosis.

Details

• Personal Author:
  Green FH ; Hu N ; Vallyathan V ; Weber KC
• Description:
  An investigation was conducted to examine the differences between the etiology and pathophysiology of two types of muscular hypertrophy in the terminal pulmonary arterial trees in coal worker's pneumoconiosis (CWP), namely longitudinally oriented and circularly oriented smooth muscle hypertrophy. For this investigation 72 autopsies without heart valvular or severe coronary lesions and without hypertensive left ventricular hypertrophy were drawn from a series of 120 unselected consecutive autopsies. The results indicated that circular smooth muscle hypertrophy in the medial wall of pulmonary arterioles demonstrated a high correlation with the incidence of right ventricular hypertrophy (RVH) in 57 CWP cases and 15 referent cases from the Appalachian region. Intimal longitudinal muscle hypertrophy, or medical circular muscle hypertrophy in small pulmonary arteries did not reveal such correlation with RVH.
• Subjects:
  Accidents, Occupational Epidemiology Occupational Exposure Occupational Health Radiation Safety Ships
• Keywords:
  Cardiovascular System Disorders Coal Dust Coal Workers Pneumoconiosis Dust Exposure Lung Disease Postmortem Examination Respiratory System Disorders
• Publisher:
  National Institute for Occupational Safety and Health
• Document Type:
  Text
• Genre:
  Conference/Symposia Proceedings
• Place as Subject:
  OSHA Region 3 ; Pennsylvania
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1526-1534
• NIOSHTIC Number:
  nn:00198721
• Citation:
  Proceedings of the VIIth International Pneumoconioses Conference, August 23-26, 1988, Pittsburgh, Pennsylvania, USA. Atlanta, GA: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, DHHS (NIOSH) Publication No. 90-108, 1990 Nov; (Part II):1526-1534
• Federal Fiscal Year:
  1991
• Peer Reviewed:
  False
• Part Number:
  II
• Source Full Name:
  Proceedings of the VIIth International Pneumoconioses Conference, August 23-26, 1988, Pittsburgh, Pennsylvania, USA
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:de61867d0014567de8544051ca45340a0ed2b0015085afd02f663a1f1540656a5a1678114004ba6ba6bfbd29bcdd15a6e5124768befbc0aab1cc6cc95a0fd76e
• Download URL:
  https://stacks.cdc.gov/view/cdc/180634/cdc_180634_DS1.pdf
• File Type:
  [PDF - 258.20 KB ]