Chemical carcinogens.

Details

• Personal Author:
  Blejer, Hector P. ; Bridbord K ; Wagoner JK
• Description:
  Occupational cancer risks from chemicals are discussed. Documentation of chemical carcinogenesis in man is difficult to obtain because cancers are not generally clinically evident until 20 to 30 years following exposure, and exposures in many workplaces are very complex. Currently there is considerable disagreement among scientists regarding the degree of exposure necessary to cause cancer. Even if a threshold of exposure could be established for individual carcinogens, it would be difficult to tabulate a worker's exposure level as he or she may be exposed to various carcinogens competing for the same target site. The recognition that an increased cancer risk exists may be brought about through epidemiologic studies and animal studies. Some recently investigated occupations include asbestos workers, auto repairmen, bakery workers, clothing pressers, coke oven workers, dairy industry workers, dental lab technicians, electricians, leather workers, photoengravers, roofers, rubber workers, and vinyl-chloride (75014) manufacturers. A tabulation is presented of confirmed and suspected occupational carcinogens by target organ. Suspected carcinogens based upon structural similarity to vinyl-chloride are listed. The use of in-vitro screening tests is noted.
• Subjects:
  Accidents, Occupational Emergencies Emergency Responders Firefighters Law Enforcement Occupational Health Personal Protective Equipment Protective Clothing Respiratory Protective Devices Safety
• Keywords:
  Bone-cancer Brain-disorders Carcinogenicity Gastrointestinal-system-disorders Hematopoietic-system Kidney-disorders Larynx-cancer Liver-cancer Lung-cancer Lymphatic-cancer Nasal-cancer Neoplasms NIOSH-Author Occupational-exposure

  More +
• Publisher:
  National Institute for Occupational Safety and Health
• Document Type:
  Text
• Funding:
  Contract
• Genre:
  Chapter
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  443-450
• NIOSHTIC Number:
  nn:00166932
• Citation:
  Occupational diseases: a guide to their recognition, revised edition. Key MM, Henschel AF, Butler J, Ligs RN, Tabershaw IR, eds. Cincinnati, OH: National Institute for Occupational Safety and Health, 1977 Jun; :443-450
• CAS Registry Number:
  Vinyl chloride (CAS RN 75-01-4)
• Editor(s):
  Key MM ; Henschel AF ; Butler J ; Ligo RN ; Tabershaw IR
• Federal Fiscal Year:
  1977
• Peer Reviewed:
  False
• Source Full Name:
  Occupational diseases: a guide to their recognition, revised edition
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:8cef1b1e5af9b49c365b2b8a8cd1e5342a997e40cd0c6e0145edbe704c8f816aab1b7822be705f2085b7e5689b85f03506e5729f0c9aef9faf0fbacd3b04ab80
• Download URL:
  https://stacks.cdc.gov/view/cdc/179842/cdc_179842_DS1.pdf
• File Type:
  [PDF - 2.10 MB ]