Engineering and other health hazard controls in oral contraceptive tablet making operations.

Details

• Personal Author:
  Anastas MY
• Description:
  A survey of health hazard controls in oral contraceptive tablet making (SIC-2834) operations was conducted. Four facilities were included in the survey. Engineering controls included using hoods while weighing pure steroids, local and general ventilation, material transfer systems in granulation and tablet forming operations, and using powder feed systems in tablet forming operations. Breathing zone estrogen and progestogen concentrations in granulation operations ranged from 0.15 to 1.04 and from 1.39 to 18.9 micrograms per cubic meter (microg/m3), respectively. Estrogen and progestogen concentrations in tablet forming operations were progestogen concentrations in packaging operations were 0.02 to 0.11 and 0.20 to 0.72microg/m3, respectively. All facilities utilized environmental and medical monitoring. Workers in granulation, tablet forming, and packaging operations were protected from exposure to steroids by respirators, coveralls, gloves, and overshoes. All facilities emphasized personal hygiene (frequent showering and changes of protective clothing). Job rotation was practiced at two facilities and good housekeeping was practiced at all facilities. The author notes that all facilities offer intensive training and education programs in health hazards, safety, and personal protective equipment associated with each job title.
• Subjects:
  Accidents, Occupational Behavior Biochemistry Carcinogens Hazardous Substances Occupational Health Safety Teratogenesis Urogenital System
• Keywords:
  Control-technology Field-Study Inhalants Lung Lung-burden Monitors NIOSH-Author NIOSH-Survey Protective-equipment Respiratory-irritants Respiratory-protection

  More +
• Publisher:
  National Institute for Occupational Safety and Health
• Document Type:
  Text
• Genre:
  Field Studies ; Control Technology
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DPSE - Division of Physical Sciences and Engineering
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  1-94
• NIOSHTIC Number:
  nn:00145199
• Citation:
  Cincinnati, OH: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, CT-105-4, 1984 Sep; :1-94
• Federal Fiscal Year:
  1984
• NORA Priority Area:
  Control-technology
• Peer Reviewed:
  False
• NAICS and SIC Codes:
  2834 - Pharmaceutical preparations - (SIC)
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:4ff337a6398e8add06e4bbcfb203ffc11821b48f877a2ee435a2654c85916c0e3893347ffcf84bdc9d54401f8477892f28a4cf0ae238d5b5c0c622a27197414e
• Download URL:
  https://stacks.cdc.gov/view/cdc/179719/cdc_179719_DS1.pdf
• File Type:
  [PDF - 2.97 MB ]