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Cost-effectiveness of Pharmaceutical-based Pandemic Influenza Mitigation Strategies1
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Feb 2010
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Source: Emerg Infect Dis. 16(2):224-230.
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Alternative Title:Emerg Infect Dis
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Description:We used a hybrid transmission and economic model to evaluate the relative merits of stockpiling antiviral drugs and vaccine for pandemic influenza mitigation. In the absence of any intervention, our base-case assumptions generated a population clinical attack rate of 31.1%. For at least some parameter values, population prepandemic vaccination strategies were effective at containing an outbreak of pandemic influenza until the arrival of a matched vaccine. Because of the uncertain nature of many parameters, we used a probabilistic approach to determine the most cost-effective strategies. At a willingness to pay of >A$24,000 per life-year saved, more than half the simulations showed that a prepandemic vaccination program combined with antiviral treatment was cost-effective in Australia.
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Volume:16
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Issue:2
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