Vibration enhancement of blood-arterial wall macromolecule transport.

Details

• Personal Author:
  Nerem RM
• Description:
  The influence of low-frequency, high-intensity, whole-body vibration on blood - arterial wall macromolecule transport has been investigated for iodine-131 labeled albumin (9006535). In-vivo studies of iodine-131-albumin uptake in the canine aorta during whole-body vibration have been carried out in anesthetized animals at a frequency of 10 hertz and with a peak to peak amplitude of 1.27 centimeters. These measurements, when compared with control measurements, indicate that during vibration there is a significant alteration in the pattern of albumin uptake in the aorta, together with an increased rate of uptake along its entire length. In-vitro studies have investigated the influence of sinusoidal pressure and flow variations on the transendothelial transport of albumin in serum perfused excised dog common carotid arteries. These results suggest that it is the vibration induced arterial wall shear stresses and a shear dependent transport process that are responsible for the enhancement of albumin uptake by the aortic wall during whole-body vibration.
• Subjects:
  Accident Prevention Accidents Accidents, Occupational Epidemiology Hunting Mortality Occupational Exposure Occupational Health Occupational Injuries Personal Protective Equipment Safety Safety Management Workplace

  More +
• Keywords:
  Biological-transport Blood-chemicals Blood-vessels Environment Physiological-effects Proteins Shear-stress
• Document Type:
  Text
• Genre:
  Conference/Symposia Proceedings
• Place as Subject:
  Ohio ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  37-43
• NIOSHTIC Number:
  nn:00074689
• Citation:
  Proceedings of the international occupational hand-arm vibration conference, October 28-31, 1975, Cincinnati, Ohio. Wasserman DE, Taylor W, Curry MG, eds. Cincinnati, OH: U.S. Department of Health, Education, and Welfare, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, DHEW (NIOSH) Publication No. 77-170, 1977 Apr; :37-43
• CAS Registry Number:
  Albumins, blood (CAS RN 9006-53-5)
• Federal Fiscal Year:
  1977
• Peer Reviewed:
  False
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:75b507d302c59220f895e3da59f275ef29447dec6b4fddbb3009da41d6714833b53431818c7d338cb02c00ed855c16119c048134f4cb45b3223dca0b2600c971
• Download URL:
  https://stacks.cdc.gov/view/cdc/178855/cdc_178855_DS1.pdf
• File Type:
  [PDF - 1023.99 KB ]