Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Rutjes, Saskia A.; Lodder, Willemijn J.; Lodder-Verschoor, Froukje; van den Berg, Harold H.J.L.; Vennema, Harry; ... More +
Rutjes, Saskia A.; Lodder, Willemijn J.; Lodder-Verschoor, Froukje; van den Berg, Harold H.J.L.; Vennema, Harry; Duizer, Erwin; Koopmans, Marion; de Roda Husman, Ana Maria; Less -
Description:
Non-travel-related hepatitis E virus (HEV) genotype 3 infections in persons in the Netherlands may have a zoonotic, foodborne, or water-borne origin. Possible reservoirs for HEV transmission by water, food, and animals were studied. HEV genotype 3/open reading frame 2 sequences were detected in 53% of pig farms, 4% of wild boar feces, and 17% of surface water samples. HEV sequences grouped within 4 genotype 3 clusters, of which 1 is so far unique to the Netherlands. The 2 largest clusters contained 35% and 43% of the animal and environmental sequences and 75% and 6%, respectively, of human HEV sequences obtained from a study on Dutch hepatitis E patients. This finding suggests that infection risk may be also dependent on transmission routes other than the ones currently studied. Besides the route of exposure, virus characteristics may be an important determinant for HEV disease in humans.
Subject:
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Animal Husbandry
Animals
Arvicolinae
Environment
Feces
Food Microbiology
Genotype
Hepatitis E
Hepatitis E Virus
Human
Humans
Netherlands
Research
Reservoir
Rivers
Rodent Diseases
Sus Scrofa
Swine
Swine Diseases
Transmission Route
Zoonoses

Source:
Emerg Infect Dis. 15(3):381-387.;
Document Type:
Journal Article;
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
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urn:sha256:2882f7c68ddf264eee4d6aa222933a026dd10359ee506ae128e39a835aedf2f6
File Type:

Supporting Files

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