Details:

Alternative Title:
Emerg Infect Dis
Personal Author:
Rutjes, Saskia A. ; Lodder, Willemijn J. ; Lodder-Verschoor, Froukje ; van den Berg, Harold H.J.L. ; Vennema, Harry ; ... More +
Rutjes, Saskia A. ; Lodder, Willemijn J. ; Lodder-Verschoor, Froukje ; van den Berg, Harold H.J.L. ; Vennema, Harry ; Duizer, Erwin ; Koopmans, Marion ; de Roda Husman, Ana Maria Less -
Description:
Non-travel-related hepatitis E virus (HEV) genotype 3 infections in persons in the Netherlands may have a zoonotic, foodborne, or water-borne origin. Possible reservoirs for HEV transmission by water, food, and animals were studied. HEV genotype 3/open reading frame 2 sequences were detected in 53% of pig farms, 4% of wild boar feces, and 17% of surface water samples. HEV sequences grouped within 4 genotype 3 clusters, of which 1 is so far unique to the Netherlands. The 2 largest clusters contained 35% and 43% of the animal and environmental sequences and 75% and 6%, respectively, of human HEV sequences obtained from a study on Dutch hepatitis E patients. This finding suggests that infection risk may be also dependent on transmission routes other than the ones currently studied. Besides the route of exposure, virus characteristics may be an important determinant for HEV disease in humans.
Subjects:
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Animal Husbandry Animals Arvicolinae Environment Feces Food Microbiology Genotype Hepatitis E Hepatitis E Virus Human Humans Netherlands Research Reservoir Rivers Rodent Diseases Sus Scrofa Swine Swine Diseases Transmission Route Zoonoses
Source:
Emerg Infect Dis. 15(3):381-387.
Document Type:
Journal Article
Collection(s):
Emerging Infectious Diseases
Main Document Checksum:
[+]
urn:sha256:2882f7c68ddf264eee4d6aa222933a026dd10359ee506ae128e39a835aedf2f6
Download URL:
https://stacks.cdc.gov/view/cdc/17660/cdc_17660_DS1.pdf
File Type:

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