Survival of infants with congenital diaphragmatic hernia in California: Impact of hospital, clinical, and sociodemographic factors

Details

• Alternative Title:
  J Perinatol
• Personal Author:
  Carmichael, Suzan L ; Ma, Chen ; Lee, Henry C ; Shaw, Gary M ; Sylvester, Karl G ; Hintz, Susan R
• Description:
  Objective. ; To understand factors associated with care and survival among babies with congenital diaphragmatic hernia (CDH). ; Study design. ; We used data on California births (2006–2011) to examine birth hospital level of care, hospital transfer before repair, and survival. ; Result. ; Among 577 infants, 25% were born at lower-level hospitals, 62% were transferred, and 31% died during infancy. Late or no prenatal care had the strongest association with birth at lower-level hospitals (adjusted Relative Risk (ARR)=1.9, 95% confidence interval (CI)=1.0–3.6). Birth at lower-level hospitals was associated with transfer (ARR=1.2, CI=1.1–1.4), and transferred infants tended to be less clinically complex. Infants with low birthweight, other birth defects, low Apgar scores, and late or no prenatal care had 2–4-fold higher risk of mortality than their comparison groups. ; Conclusions. ; These data support the importance of prenatal care and delivery planning into higher-level hospitals for optimal care and outcomes for newborns with CDH.
• Subjects:
  • California
  • Female
  • Hernias, Diaphragmatic, Congenital
  • Hospitals
  • Humans
  • Infant
  • Infant, Newborn
  • Pregnancy
  • Prenatal Care
  • Survival Rate
• Source:
  J Perinatol. 40(6):943-951
• Pubmed ID:
  32086437
• Pubmed Central ID:
  PMC7260105
• Document Type:
  Journal Article
• Funding:
  R01 MD007796/MD/NIMHD NIH HHSUnited States/ ; U01 DD001226/DD/NCBDD CDC HHSUnited States/
• Volume:
  40
• Issue:
  6
• Download URL:
  https://stacks.cdc.gov/view/cdc/175287/cdc_175287_DS1.pdf
• File Type:
  [PDF - 114.10 KB]
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:78c5459b324255a4a71208230022c273f292a2a5c4ef875022a614992c349c3a2968123a2b55c41cc2e6d06970056a5665d7afc916a8932d42371b82ccb56824