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Cost-effectiveness of expanded latent TB infection testing and treatment: Lynn City, Massachusetts, USA
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1 01 2024
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Source: Int J Tuberc Lung Dis. 28(1):21-28
[PDF-399.02 KB]
Details:
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Alternative Title:Int J Tuberc Lung Dis
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Personal Author:
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Description:BACKGROUND:
Between October 2016 and March 2019, Lynn Community Health Center in Massachusetts implemented a targeted latent TB infection testing and treatment (TTT) program, increasing testing from a baseline of 1,200 patients tested to an average of 3,531 patients tested, or 9% of the population per year.
METHODS:
We compared pre-implementation TTT, represented by the first two quarters of implementation data, to TTT, represented by 12 quarters of data. Time, diagnostic, and laboratory resources were estimated using micro-costing. Other cost and testing data were obtained from the electronic health record, pharmaceutical claims, and published reimbursement rates. A Markov cohort model estimated future health outcomes and cost-effectiveness from a societal perspective in 2020 US dollars. Monte Carlo simulation generated 95% uncertainty intervals.
RESULTS:
The TTT program exhibited extended dominance over baseline pre-intervention testing and had an incremental cost-effectiveness ratio (ICER) of US$52,603 (US$22,008–US$95,360). When compared to baseline pre-TTT testing, the TTT program averted an estimated additional 7.12 TB cases, 3.49 hospitalizations, and 0.16 deaths per lifetime cohort each year.
CONCLUSIONS:
TTT was more cost-effective than baseline pre-implementation testing. Lynn Community Health Center’s experience can help inform other clinics considering expanding latent TB infection testing.
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Pubmed ID:38178297
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Pubmed Central ID:PMC11149049
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Volume:28
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Issue:1
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