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In-Depth Lab Report: Evaluation of a Nanomaterial Handling Enclosure Conducted at the Alice Hamilton Laboratories
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2013/11/01
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Description:Many users have adopted the laboratory fume hood as the primary exposure control given its ubiquitous nature and history as a standard control used in most research laboratories. New lower flow hoods are being marketed and used for the manipulation of nanomaterials. The use of lower flows may reduce the impact of turbulence and the body wake on the potential for fume hood leakage. However, there is little information on their performance. A study was conducted by engineers at the NIOSH Alice Hamilton Labs to evaluate the performance of a new "nano" fume hood under varying room ventilation conditions and for three different exhaust flows. For the study, a tracer gas test protocol adapted from the European fume hood test method was used (European Committee for Standardization (CEN) 2003). A static test procedure using a full-size manikin was conducted. Samplers were placed in the manikin breathing zone as well as at the left and right corner of the hood to assess potential leakage at areas known to have high turbulence. Hood exhaust flow rates of 242, 348 and 445 ft3/min were used to represent a range of average hood face velocities of 59, 81 and 96 ft/min, respectively. In addition, all conditions were tested with the room air conditioner on and off to assess the impact of the supply air on the hood's containment effectiveness. During the tracer gas tests conducted in this study, leakage out of the hood was only noted when the room air conditioner was on. Hood face velocity measurements showed that temporal variations increased when the room air conditioner was on resulting in an increase in turbulence intensity, especially near the side of the hood adjacent to the supply air diffuser. When the room air conditioner was turned off, tracer gas tests showed good containment across all hood exhaust flows. However, when the room air conditioner was turned on, the tracer gas tests showed leakage for both the low and medium exhaust flows. This indicates that the additional turbulence created by a diffuser above the hood can result in leakage even with face velocities in the range recommended by consensus standards.
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Pages in Document:1-16
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NIOSHTIC Number:nn:20048782
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NTIS Accession Number:PB2017-100464
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Citation:Cincinnati, OH: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control and Prevention, National Institute for Occupational Safety and Health, EPHB 364-11a, 2013 Nov;:1-16;
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Federal Fiscal Year:2014
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Peer Reviewed:False
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