Relapse Associated with Active Disease Caused by Beijing Strain of Mycobacterium tuberculosis1

Burman, William J.; Bliven, Erin E.; Cowan, Lauren; Bozeman, Lorna; Nahid, Payam; Diem, Lois; Vernon, Andrew

Back to Previous Page

- Add this to...
- Twitter
- Facebook
- Google Bookmarks
- LinkedIn

Relapse Associated with Active Disease Caused by Beijing Strain of Mycobacterium tuberculosis1

Published Date:

Jul 2009

Source:

Emerg Infect Dis. 15(7):1061-1067.

[PDF - 555.90 KB]

Details:

Personal Authors:

Burman, William J. ; Bliven, Erin E. ; Cowan, Lauren ; Bozeman, Lorna ; Nahid, Payam ; ... More ▼

Corporate Authors:

for the Tuberculosis Trials Consortium

Keywords:

[+]

Description:

The role of microbial factors in outcomes of tuberculosis treatment has not been well studied. We performed a case-control study to evaluate the association between a Beijing strain and tuberculosis treatment outcomes. Isolates from patients with culture-positive treatment failure (n = 8) or relapse (n = 54) were compared with isolates from randomly selected controls (n = 296) by using spoligotyping. Patients with Beijing strains had a higher risk for relapse (odds ratio [OR] 2.0, 95% confidence interval [CI] 1.0-4.0, p = 0.04) but not for treatment failure. Adjustment for factors previously associated with relapse had little effect on the association between Beijing strains and relapse. Beijing strains were strongly associated with relapse among Asian-Pacific Islanders (OR 11, 95% CI 1.1-108, p = 0.04). Active disease caused by a Beijing strain was associated with increased risk for relapse, particularly among Asian-Pacific Islanders.

Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases

Supporting Files:

08-1253-F.gif	image/gif
08-1253-F.jpg	image/jpeg
08-1253_finalR.nxml	text/plain
license.txt	text/plain

No Related Documents.

You May Also Like:

Pulmonary Disease Caused by Mycobacterium marseillense, Italy

Personal Author:

Grottola, Antonella; Roversi, Pietro; Fabio, Anna; Antenora, Federico; Apice, Mariagrazia; Tagliazucchi, Sara; Gennari, William; Serpini, Giulia Fregni; Rumpianesi, Fabio; Fabbri, Leonardo M.; Magnani, Rita; Pecorari, Monica;

Published:

Oct 2014

Source:

Emerg Infect Dis. 20(10):1769-1770.

File Type:

[PDF - 308.22 KB]
Mycobacterium tuberculosis Beijing Genotype and Risk for Treatment Failure and Relapse, Vietnam

Personal Author:

Lan, Nguyen Thi Ngoc; Lien, Hoang Thi Kim; Tung, Le B.; Borgdorff, Martien W.; Kremer, Kristin; van Soolingen, Dick;

Published:

Dec 2003

Source:

Emerg Infect Dis. 9(12):1633-1635.

Description:

Among 2,901 new smear-positive tuberculosis cases in Ho Chi Minh City, Vietnam, 40 cases of treatment failure and 39 relapsing cases were diagnosed. All initial and follow-up Mycobacterium tuberculosis isolates of these case-patients had (nearly) ide...

File Type:

[PDF - 194.75 KB]
Mycobacterium tuberculosis Beijing genotype strains associated with febrile response to treatment.

Personal Author:

van Crevel, R.; Nelwan, R. H.; de Lenne, W.; Veeraragu, Y.; van der Zanden, A. G.; Amin, Z.; van der Meer, J. W.; van Soolingen, D.;

Published:

2001 Sep-Oct

Source:

Emerg Infect Dis. 7(5):880-883.

Description:

DNA fingerprinting has demonstrated predominance of the Beijing genotype among Mycobacterium tuberculosis strains isolated in Southeast Asia. We prospectively examined the occurrence of Beijing genotype strains in tuberculosis patients in Indonesia. ...

File Type:

[PDF - 70.24 KB]
Mycobacterium tuberculosis Beijing Strain, Bamako, Mali

Personal Author:

Diarra, Bassirou; Siddiqui, Sophia; Sogoba, Dramane; Traore, Brehima; Maiga, Mamoudou; Washington, Janice; Tounkara, Anatole; Polis, Michael A.;

Published:

Feb 2010

Source:

Emerg Infect Dis. 16(2):362-363.

File Type:

[PDF - 89.82 KB]
Diphtheria-like Disease Caused by Toxigenic Corynebacterium ulcerans Strain

Personal Author:

Sangal, Vartul; Nieminen, Leena; Weinhardt, Barbara; Raeside, Jane; Tucker, Nicholas P.; Florea, Catalina-Diana; Pollock, Kevin G.; Hoskisson, Paul A.;

Published:

Jul 2014

Source:

Emerg Infect Dis. 20(7):1257-1258.

File Type:

[PDF - 344.95 KB]