Recurrent Zoonotic Transmission of Nipah Virus into Humans, Bangladesh, 2001–2007

Luby, Stephen P.; Hossain, M. Jahangir; Gurley, Emily S.; Ahmed, Be-Nazir; Banu, Shakila; Khan, Salah Uddin; Homaira, Nusrat; Rota, Paul A.; Rollin, Pierre E.; Comer, James A.; Kenah, Eben; Ksiazek, Thomas G.; Rahman, Mahmudur

Back to Previous Page

- Add this to...
- Twitter
- Facebook
- Google Bookmarks
- LinkedIn

Recurrent Zoonotic Transmission of Nipah Virus into Humans, Bangladesh, 2001–2007

Published Date:

Aug 2009

Source:

Emerg Infect Dis. 15(8):1229-1235.

[PDF - 563.38 KB]

Details:

Personal Authors:

Luby, Stephen P. ; Hossain, M. Jahangir ; Gurley, Emily S. ; Ahmed, Be-Nazir ; Banu, Shakila ; ... More ▼

Keywords:

[+]

Description:

Human Nipah outbreaks recur in a specific region and time of year in Bangladesh. Fruit bats are the reservoir host for Nipah virus. We identified 23 introductions of Nipah virus into human populations in central and northwestern Bangladesh from 2001 through 2007. Ten introductions affected multiple persons (median 10). Illness onset occurred from December through May but not every year. We identified 122 cases of human Nipah infection. The mean age of case-patients was 27 years; 87 (71%) died. In 62 (51%) Nipah virus-infected patients, illness developed 5-15 days after close contact with another Nipah case-patient. Nine (7%) Nipah case-patients transmitted virus to others. Nipah case-patients who had difficulty breathing were more likely than those without respiratory difficulty to transmit Nipah (12% vs. 0%, p = 0.03). Although a small minority of infected patients transmit Nipah virus, more than half of identified cases result from person-to-person transmission. Interventions to prevent virus transmission from bats to humans and from person to person are needed.

Document Type:

Journal Article

Collection(s):

Emerging Infectious Diseases

Supporting Files:

08-1237-F1.gif	image/gif
08-1237-F1.jpg	image/jpeg
08-1237-F2.gif	image/gif
08-1237-F2.jpg	image/jpeg
08-1237-F3.gif	image/gif
08-1237-F3.jpg	image/jpeg
08-1237_finalR.nxml	text/plain
license.txt	text/plain

No Related Documents.

You May Also Like:

Convergence of Humans, Bats, Trees, and Culture in Nipah Virus Transmission, Bangladesh

Personal Author:

Gurley, Emily S.; Hegde, Sonia T.; Hossain, Kamal; Sazzad, Hossain M.S.; Hossain, M. Jahangir; Rahman, Mahmudur; Sharker, M.A. Yushuf; Salje, Henrik; Islam, M. Saiful; Epstein, Jonathan H.; Khan, Salah U.; Kilpatrick, A. Marm; Daszak, Peter; Luby, Stephen P.;

Published:

Sep 2017

Source:

Emerg Infect Dis. 23(9):1446-1453.

Description:

Preventing emergence of new zoonotic viruses depends on understanding determinants for human risk. Nipah virus (NiV) is a lethal zoonotic pathogen that has spilled over from bats into human populations, with limited person-to-person transmission. We ...

File Type:

[PDF - 1.83 MB]
Foodborne Transmission of Nipah Virus, Bangladesh

Personal Author:

Luby, Stephen P.; Rahman, Mahmudur; Hossain, M. Jahangir; Blum, Lauren S.; Husain, M. Mushtaq; Gurley, Emily; Khan, Rasheda; Ahmed, Be-Nazir; Rahman, Shafiqur; Nahar, Nazmun; Kenah, Eben; Comer, James A.; Ksiazek, Thomas G.;

Published:

Dec 2006

Source:

Emerg Infect Dis. 12(12):1888-1894.

Description:

We investigated an outbreak of encephalitis in Tangail District, Bangladesh. We defined case-patients as persons from the outbreak area in whom fever developed with new onset of seizures or altered mental status from December 15, 2004, through Januar...

File Type:

[PDF - 191.13 KB]
Nipah Virus Transmission from Bats to Humans Associated with Drinking Traditional Liquor Made from Date Palm Sap, Bangladesh, 2011–2014

Personal Author:

Islam, M. Saiful; Sazzad, Hossain M.S.; Satter, Syed Moinuddin; Sultana, Sharmin; Hossain, M. Jahangir; Hasan, Murshid; Rahman, Mahmudur; Campbell, Shelley; Cannon, Deborah L.; Ströher, Ute; Daszak, Peter; Luby, Stephen P.; Gurley, Emily S.;

Published:

Apr 2016

Source:

Emerg Infect Dis. 22(4):664-670.

Description:

Nipah virus (NiV) is a paramyxovirus, and Pteropus spp. bats are the natural reservoir. From December 2010 through March 2014, hospital-based encephalitis surveillance in Bangladesh identified 18 clusters of NiV infection. The source of infection for...

File Type:

[PDF - 442.38 KB]
Integrated cluster- and case-based surveillance for detecting stage III zoonotic pathogens: an example of Nipah virus surveillance in Bangladesh

Personal Author:

NASER, A. M.; HOSSAIN, M. J.; SAZZAD, H. M. S.; HOMAIRA, N.; GURLEY, E. S.; PODDER, G.; AFROJ, S.; BANU, S.; ROLLIN, P. E.; DASZAK, P.; AHMED, B.-N.; RAHMAN, M.; LUBY, S. P.;

Published:

Oct 24 2014

Source:

Epidemiol Infect. 2014; 143(9):1922-1930.

Description:

This paper explores the utility of cluster- and case-based surveillance established in government hospitals in Bangladesh to detect Nipah virus, a stage III zoonotic pathogen. Physicians listed meningo-encephalitis cases in the 10 surveillance hospit...

File Type:

[PDF - 292.94 KB]
Genetic Characterization of Nipah Virus, Bangladesh, 2004

Personal Author:

Harcourt, Brian H.; Lowe, Luis; Tamin, Azaibi; Liu, Xin; Bankamp, Bettina; Bowden, Nadine; Rollin, Pierre E.; Comer, James A.; Ksiazek, Thomas G.; Hossain, Mohammed Jahangir; Gurley, Emily S.; Breiman, Robert F.; Bellini, William J.; Rota, Paul A.;

Published:

Oct 2005

Source:

Emerg Infect Dis. 11(10):1594-1597.

Description:

Until 2004, identification of Nipah virus (NV)-like outbreaks in Bangladesh was based on serology. We describe the genetic characterization of a new strain of NV isolated during outbreaks in Bangladesh (NV-B) in 2004, which confirms that NV was the e...

File Type:

[PDF - 141.53 KB]