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Nosocomial bacteremias associated with intravenous fluid therapy - USA
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March 6, 1971
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Series: MMWR; v. 20, no. 9, Suppl.
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Description:Between October 1970 and March 1, 1971, eight U.S. Hospitals in seven states experienced 150 bacteremias caused by Enterobacter cloacae or Gram-negative organisms of the Erwinia group. There were nine deaths; all were associated with intravenous (IV) fluid therapy. The Enterobacter bacteremias in all hospitals were substantially increased as compared to previous time periods. Four hospitals which isolated and identified Erwinia had not previously encountered infections with these organisms. In-depth epidemiologic investigations were performed in three of the hospitals (Figure 1).
All eight hospitals utilize fluids and systems manufactured by Abbott Laboratories, which produces approximately 45 percent of all IV fluids sold within the U.S. In approximately 30 cases, the same organisms were isolated from blood cultures and contaminated in Use IV fluids. In hospital B (see arrow, Figure 1) no further cases were observed after discontinuance of Abbott products.
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