HHE 76-36-369 Supplemental Report: (Follow Up Medical Study to HHE 76-36-339): Eagle Picher Industries, Inc.: Joplin, Missouri

Details

• Personal Author:
  Baker, Edward L. Jr.
• Corporate Authors:
  National Institute for Occupational Safety and Health
• Description:
  Results are presented of outpatient diagnostic studies performed by a board-certified nephrologist in 19 of 53 affected workers in whom an earlier NIOSH Health Hazard Evaluation, No. 76-036-0339, of lead (7439921) exposure at the Eagle Picher Industries, Lead Chemicals Plant (SIC-2819) in Joplin, Missouri established the presence of high blood urea nitrogen levels. Physical examinations were generally within normal limits, but the results of kidney function tests, blood lead levels, erythrocyte protoporphyrin, urinary delta- aminolevulinic-acid (106605) levels, the presence of anemia and high urinary beta-2-microglobulin levels in 7 of the workers tested demonstrated a significantly increased prevalence of moderately severe kidney disease in employees at the Eagle Picher plant in Joplin, Missouri. All workers had a history of heavy lead exposure for 5-30 years. A positive relationship was established between the degree of renal dysfunction and duration of lead exposure. Periodic screening of other lead exposed workers is indicated to detect early lead related renal disease, which could best be accomplished by measuring creatinine clearance and urinary concentrating ability every six months. [Description provided by NIOSH]
• Subjects:
  Biochemistry Blood Diagnosis Hematologic Diseases Hematologic Tests Kidney Diseases Lead Lead Poisoning Metals Metals, Heavy Nervous System Diseases Occupational Health Poisoning Preventive Medicine Safety Toxicology Urine Urogenital Diseases Urogenital System

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• Keywords:
  Anemia Blood-chemistry Blood-disorders Blood Lead Clinical-tests Diagnostic-tests Hazard-Unconfirmed Heavy-metals HHE-76-36-339 HHE-76-36-369 Kidney-disorders Kidney Disease Lead-poisoning Lead Intoxication Lead Toxicity Metal-poisoning NIOSH-Author NIOSH-Health-Hazard-Evaluation OSHA Region 7 Peripheral Neuropathy Preventive-medicine Urine-chemistry

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• Series:
  Health Hazard Evaluation Reports (HHE)
• DOI:
  https://doi.org/10.26616/NIOSHHHE7636369
• Publisher:
  National Institute for Occupational Safety and Health
• Document Type:
  Text
• Genre:
  Field Study
• Place as Subject:
  Missouri ; Joplin (MO) ; OSHA Region 7
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  11 pdf pages
• Contributor:
  Browning, David Jr. ; Ligo, Robert N.
• NIOSHTIC Number:
  nn:00069415
• NTIS Accession Number:
  PB-270947
• Citation:
  Cincinnati, OH: U.S. Department of Health, Education, and Welfare, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, HHE 76-36-369, 1977 Mar ; :1-10
• CAS Registry Number:
  Lead (CAS RN 7439-92-1)
• Federal Fiscal Year:
  1977
• Peer Reviewed:
  False
• NAICS and SIC Codes:
  2819 - Industrial inorganic chemicals, not elsewhere classified - (SIC)
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:fda84f400b010eafa14d8275c7792708bf3d1ac8f7b832ecbce78b071d0d2fcfae943221f1c56ca3efcbc66419ac271d3c876a72ffb53e7f3312bcebb5149341
• Download URL:
  https://stacks.cdc.gov/view/cdc/173958/cdc_173958_DS1.pdf
• File Type:
  [PDF - 1.46 MB ]