Content
and Copyright
i
Simian T-Lymphotropic Virus Diversity among Nonhuman Primates, Cameroon
-
Published Date:
Feb 2009
Source:Emerg Infect Dis. 15(2):175-184.
[PDF-274.82 KB]
Details:
-
Alternative Title:Emerg Infect Dis
-
Personal Author:
-
Description:Cross-species transmission of retroviruses is common in Cameroon. To determine risk for simian T-cell lymphotropic virus (STLV) transmission from nonhuman primates to hunters, we examined 170 hunter-collected dried blood spots (DBS) from 12 species for STLV. PCR with generic tax and group-specific long terminal repeat primers showed that 12 (7%) specimens from 4 nonhuman primate species were infected with STLV. Phylogenetic analyses showed broad diversity of STLV, including novel STLV-1 and STLV-3 sequences and a highly divergent STLV-3 subtype found in Cercopithecus mona and C. nictitans monkeys. Screening of peripheral blood mononuclear cell DNA from 63 HTLV-seroreactive, PCR-negative hunters did not identify human infections with this divergent STLV-3. Therefore, hunter-collected DBS can effectively capture STLV diversity at the point where pathogen spillover occurs. Broad screening using this relatively easy collection strategy has potential for large-scale monitoring of retrovirus cross-species transmission among highly exposed human populations.
-
Subject:
-
Document Type:
-
Place as Subject:
-
Collection(s):
-
Main Document Checksum:
- File Type:
-
Supporting Files:
image/gif 
image/jpeg 
image/gif 
image/jpeg 
text/plain
text/plain 
image/gif 
image/jpeg 
image/gif 
image/jpeg 
image/gif 
image/jpeg 
image/gif 
image/jpeg
No Related Documents.
You May Also Like:
-
Published Date:Source:Description:File Type:[PDF - 222.16 KB]
File Type:[PDF - 222.16 KB]
Published Date:Source:File Type:[PDF - 209.44 KB]
File Type:[PDF - 209.44 KB]
Published Date:Source:Description:File Type:[PDF - 1.30 MB]
File Type:[PDF - 1.30 MB]
Published Date:Source:Description:File Type:[PDF - 1.58 MB]
File Type:[PDF - 1.58 MB]
Published Date:Source:Description:File Type:[PDF - 260.41 KB]
File Type:[PDF - 260.41 KB]
Have Questions?
Visit CDC Info
Email
CDC-INFO
Open 24/7
CDC INFORMATION
CONNECT WITH CDC
