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Rensselaer, New York
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1984/01/01
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Description:The incidence of dermatitis due to p-nitrobenzyl-bromide (100118) (PNB) exposure was investigated on September 30, 1980, at Sterling Organics (SIC-0286), Rensselaer, New York. The evaluation was requested by the International Chemical Workers Union on behalf of about 15 PNB production workers. Work practices and processes were evaluated, and wipe samples collected from various work surfaces were analyzed for PNB, p-nitrobenzyl-amine (7409305) (PNA), and p- nitrobenzyl-alcohol (619738). Workers were examined for dermatitis and medical records were reviewed. The washing agents used for removal of PNB from the skin were compared to the 2 percent ammonia in water solution used at the facility. Only one sample contained a detectable amount of p-nitrobenzyl-alcohol. None of the samples contained detectable amounts of PNB or PNA. None of the workers had dermatitis at the time of the study, and no cases had been reported since the company began spraying potentially contaminated surfaces with the ammonia solution. The three alternate solutions were not as effective as the ammonia solution in removing PNB from the skin. The authors conclude that PNB is an intense primary irritant and sensitizer
however, current engineering controls and work practices appear to provide adequate protection.
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Pages in Document:20 pdf pages
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NIOSHTIC Number:nn:00149677
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NTIS Accession Number:PB85-179232
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Citation:Cincinnati, OH: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, HETA 80-242-1106, 1984 Jan;:1-8;
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Federal Fiscal Year:1984
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Peer Reviewed:False
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