Health Hazard Evaluation Report: HETA-84-339-2052: Westinghouse Electric Company; Bloomington, Indiana

Details

• Personal Author:
  Bernert, John T. ; Hannon, W. Harry ; Smith, Alexander B. ; Steele, Gregory
• Corporate Authors:
  National Institute for Occupational Safety and Health
• Description:
  In response to a request from the Indiana State Board of Health, a follow up study was conducted of workers occupationally exposed to polychlorinated-biphenyls (1336363) (PCBs) at the Westinghouse Electric Corporation's Transmission and Distribution Components Division (SIC-3629), Bloomington, Indiana. A cross sectional study had been conducted in 1977. Workers in the high and low serum PCB groups from that study were invited to participate
  
  60 of 66 workers originally studied participated in this study. Those in the high-level group were on the average 5.6 years older than the low PCB group. Use of PCBs was discontinued in 1977. By 1985 the levels of serum PCB concentrations in the low group had decreased by an average of 85% of the 1977 value. Levels in the high PCB group had decreased by an average of 90%. No clinical abnormalities attributable to PCB exposure were noted. Serum PCB levels were positively and significantly correlated with triglycerides, cholesterol, total bilirubin, conjugated bilirubin, beta- glucuronidase, 5'-nucleotidase, serum apolipoprotein-Al, serum apolipoprotein-B, urinary creatinine, and urinary alanine- aminopeptidase. According to the authors, the biochemical findings are indicative of the physiological effects of PCBs on lipid metabolism, liver function and kidney function. The clinical significance of these findings 8 years after occupational exposures had ceased is unknown.
  
  
• Subjects:
  Blood Enzymes Hematologic Tests Hydrocarbons Occupational Exposure Occupational Health Polycyclic Aromatic Hydrocarbons Safety
• Keywords:
  Aroclor Aromatic-hydrocarbons Blood-analysis Chlorinated-hydrocarbons Electrical Industrial Apparatus, Not Elsewhere Classified Enzyme-activity Hazard-Unconfirmed HETA-84-339-2052 NIOSH-Author NIOSH-Health-Hazard-Evaluation NIOSH-Technical-Assistance-Report Occupational-exposure OSHA Region 5 PCB Polychlorinated Biphenyls

  More +
• Series:
  Health Hazard Evaluation Reports (HHE)
• Subseries:
  Health Evaluation and Technical Assistance (HETA)
• DOI:
  https://doi.org/10.26616/NIOSHHETA843392052
• Publisher:
  National Institute for Occupational Safety and Health
• Document Type:
  Text
• Genre:
  Field Study
• Place as Subject:
  Indiana ; OSHA Region 5
• CIO:
  National Institute for Occupational Safety and Health (NIOSH)
• Division:
  DSHEFS - Division of Surveillance, Hazard Evaluations, and Field Studies
• Topic:
  Workplace Safety & Health
• Location:
  North America
• Pages in Document:
  103 pdf pages
• Contributor:
  Coleman, Marian E. ; Collins, James
• NIOSHTIC Number:
  nn:00194757
• NTIS Accession Number:
  PB91-115766
• Citation:
  Cincinnati, Ohio: U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, HETA 84-339-2052, 1990 Jun ; :1-104
• CAS Registry Number:
  Polychlorinated biphenyl(s)-PCB(s) (CAS RN 1336-36-3)
• Federal Fiscal Year:
  1990
• Peer Reviewed:
  False
• NAICS and SIC Codes:
  3629 - Electrical industrial apparatus, not elsewhere classified - (SIC)
• Collection(s):
  National Institute for Occupational Safety and Health
• Main Document Checksum:
  urn:sha-512:6e6c3d9a3e29dcffb0e52c429851d7e610b839ff5933503a485c02bec9fa97c42fa4dcce1ddb624007a0248056a5115023c51106b55c6c4c9bfd648d5fb1e351
• Download URL:
  https://stacks.cdc.gov/view/cdc/171744/cdc_171744_DS1.pdf
• File Type:
  [PDF - 11.40 MB ]