In vitro Testing of Trichomonas vaginalis Drug Susceptibility: Evaluation of Minimal Lethal Concentration for Secnidazole that Correlates with Treatment Success

Graves, Keonte J.; Novak, Jan; Tiwari, Hemant; Secor, W. Evan; Augostini, Peter; Muzny, Christina A.

doi:10.1097/OLQ.0000000000001992

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CDC STACKS serves as an archival repository of CDC-published products including scientific findings, journal articles, guidelines, recommendations, or other public health information authored or co-authored by CDC or funded partners. As a repository, CDC STACKS retains documents in their original published format to ensure public access to scientific information.

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In vitro Testing of Trichomonas vaginalis Drug Susceptibility: Evaluation of Minimal Lethal Concentration for Secnidazole that Correlates with Treatment Success

11 01 2024
By Graves, Keonte J. ; Novak, Jan ; Tiwari, Hemant ; ...
http://dx.doi.org/10.1097/OLQ.0000000000001992
Source: Sex Transm Dis. 51(11):e43-e45

[PDF-411.52 KB]

English

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Details:

Alternative Title:

Sex Transm Dis
Personal Author:

Graves, Keonte J. ; Novak, Jan ; Tiwari, Hemant ; Secor, W. Evan ; Augostini, Peter ; ... More +

Graves, Keonte J. ; Novak, Jan ; Tiwari, Hemant ; Secor, W. Evan ; Augostini, Peter ; Muzny, Christina A. Less -
Description:

We determined the in vitro minimum lethal concentration of secnidazole and assessed the correlation with clinical susceptibility among Trichomonas vaginalis isolates obtained from 71 women, of whom 66 were successfully treated with this medication. A minimum lethal concentration ≤12.5 μg/mL correlated with clinical susceptibility in this study.
Subjects:

[+]

Adult Antiprotozoal Agents Female Humans Metronidazole Microbial Sensitivity Tests Parasitic Sensitivity Tests Treatment Outcome Trichomonas Vaginalis Trichomonas Vaginitis
Keywords:

[+]

5-nitroimidazoles Drug Resistance Minimum Lethal Concentration Secnidazole
Source:

Sex Transm Dis. 51(11):e43-e45
Pubmed ID:

38687328
Pubmed Central ID:

PMC11522018
Document Type:

Journal Article
Funding:

CC999999/ImCDC/Intramural CDC HHSUnited States/ ; F31 AI161785/AI/NIAID NIH HHSUnited States/

CC999999/ImCDC/Intramural CDC HHSUnited States/ ; F31 AI161785/AI/NIAID NIH HHSUnited States/ Less -
Volume:

51
Issue:

11
Collection(s):

CDC Public Access
Main Document Checksum:

[+]

urn:sha-512:b985c213f387fe179f3f58824bc3367dbb2a4eb65bc2b6257cc7c909e24f4c56352a677a973a176549978735ff03534f2fb0c8162fe3a749df4965f3fc70a931
Download URL:

https://stacks.cdc.gov/view/cdc/168881/cdc_168881_DS1.pdf
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	nihms-2012039-f0001.gif	gif
	nihms-2012039-f0001.jpg	jpeg
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	NIHMS2012039-supplement-1.pdf	pdf

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