Factors associated with pityriasis versicolor in a large national database

Details

• Alternative Title:
  Mycoses
• Personal Author:
  Hill, Rachel C. ; De Faria, Willian ; Gold, Jeremy A. W. ; Lipner, Shari R.
• Description:
  Background:
  
  Pityriasis versicolor (PV), a cutaneous fungal infection, most commonly affects adolescents and young adults and is associated with hyperhidrosis and humid weather. Understanding other factors associated with PV might help improve diagnostic and treatment practices.
  
  Objectives:
  
  PV’s associations with patient demographics, comorbidities and medication exposures were assessed using the All of Us Database, a large, diverse, national database from the United States.
  
  Methods:
  
  A case–control study with multivariable analysis was performed.
  
  Results:
  
  We identified 456 PV case-patients and 1368 control-patients. PV case-patients (vs. control-patients) were younger (median age [years] (standard deviation): 48.7 (15.4) vs. 61.9 (15.5); OR: 0.95, CI: 0.94–0.96) and more likely to be men versus women (42.8% vs. 33.9%, OR: 1.45, CI: 1.16–1.79) and Black (19.5% vs. 15.8%, OR: 1.35, 95% CI: 1.02–1.80) or Asian (4.6% vs. 2.7%, OR: 1.86, CI: 1.07–3.24) versus White. PV case-patients more frequently had acne (5.3% vs. ≤1.5%, OR: 5.37, CI: 2.76–10.48) and less frequently had type 2 diabetes mellitus (T2DM) (14.7% vs. 24.7%, OR: 0.52, CI: 0.39–0.70) and hypothyroidism (OR: 10.3% vs. 16.4%, OR: 0.59, CI: 0.42–0.82). In multivariable analysis, PV odds were significantly higher in those with acne and lower in those with T2DM, older age and female sex.
  
  Conclusions:
  
  Our results may be used as a basis for future studies evaluating whether acne treatment may decrease PV risk. Physicians could educate patients with acne about PV, including strategies to control modifiable PV risk factors, such as avoidance of hot and humid environments and avoidance of use of topical skin oils.
  
  
• Subjects:
  Adolescent Adult Aged Case-Control Studies Comorbidity Databases, Factual Female Humans Male Middle Aged Risk Factors Tinea Versicolor United States Young Adult

  More +
• Keywords:
  Acne Age All Of Us Female Hypothyroidism Pityriasis Versicolor Sex Tinea Versicolor Type 2 Diabetes Mellitus
• Source:
  Mycoses. 67(8):e13775
• Pubmed ID:
  39079943
• Pubmed Central ID:
  PMC11409176
• Document Type:
  Journal Article
• Funding:
  OT2 OD026556/OD/NIH HHSUnited States/ ; U2C OD023196/OD/NIH HHSUnited States/ ; OT2 OD025315/OD/NIH HHSUnited States/ ; OT2 OD026551/OD/NIH HHSUnited States/ ; U24 OD023121/OD/NIH HHSUnited States/ ; OT2 OD026552/OD/NIH HHSUnited States/ ; OT2 OD026549/OD/NIH HHSUnited States/ ; OT2 OD025337/OD/NIH HHSUnited States/ ; OT2 OD025277/OD/NIH HHSUnited States/ ; OT2 OD026555/OD/NIH HHSUnited States/ ; OT2 OD026553/OD/NIH HHSUnited States/ ; OT2 OD023205/OD/NIH HHSUnited States/ ; OT2 OD025276/OD/NIH HHSUnited States/ ; OT2 OD026557/OD/NIH HHSUnited States/ ; OT2 OD026554/OD/NIH HHSUnited States/ ; U24 OD023163/OD/NIH HHSUnited States/ ; OT2 OD023206/OD/NIH HHSUnited States/ ; U24 OD023176/OD/NIH HHSUnited States/ ; OT2 OD026548/OD/NIH HHSUnited States/ ; OT2 OD026550/OD/NIH HHSUnited States/ ; CC999999/ImCDC/Intramural CDC HHSUnited States/
• Volume:
  67
• Issue:
  8
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:e5dfdb2d800bf40847f83236ffb6b30bd3249ab4d5cfbe96463ce367e6e11e6b7dd4cc7929e09021c620bf21a27151a829a077fa6b6880a905b565d974931f66
• Download URL:
  https://stacks.cdc.gov/view/cdc/162426/cdc_162426_DS1.pdf
• File Type:
  [PDF - 72.44 KB ]