Campylobacter jejuni Multilocus Sequence Types in Humans, Northwest England, 2003–2004

Details

• Alternative Title:
  Emerg Infect Dis
• Personal Author:
  Sopwith, Will ; Birtles, Andrew ; Matthews, Margaret ; Fox, Andrew ; Gee, Steven ; Painter, Michael ; Regan, Martyn ; Syed, Qutub ; Bolton, Eric
• Description:
  Detailed understanding of the epidemiology of Campylobacter is increasingly facilitated through use of universal and reproducible techniques for accurate strain differentiation and subtyping. Multilocus sequence typing (MLST) enables discriminatory subtyping and grouping of isolate types into genetically related clonal complexes; it also has the advantage of ease of application and repeatability. Recent studies suggest that a measure of host association may be distinguishable with this system. We describe the first continuous population-based survey to investigate the potential of MLST to resolve questions of campylobacteriosis epidemiology. We demonstrate the ability of MLST to identify variations in the epidemiology of campylobacteriosis between distinct populations and describe the distribution of key subtypes of interest.
• Subjects:
  Adolescent Adult Age Factors Bacterial Typing Techniques Base Sequence Campylobacter Campylobacter Infections Campylobacter Jejuni Child Child, Preschool England Epidemiology Epidemiology, Molecular Great Britain Humans Infant Infant, Newborn Middle Aged Multilocus Sequence Typing Research Seasons

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• Source:
  Emerg Infect Dis. 12(10):1500-1507.
• Document Type:
  Journal Article
• Volume:
  12
• Issue:
  10
• Collection(s):
  Emerging Infectious Diseases
• Main Document Checksum:
  urn:sha256:d4ef94d6491b52db4d756e3954a45babc14fe107e3380c35658ddfa6f22f9512
• Download URL:
  https://stacks.cdc.gov/view/cdc/16209/cdc_16209_DS1.pdf
• File Type:
  [PDF - 284.26 KB ]