A digital, coach-assisted intervention to address the psychosocial needs of young adult cancer survivors: randomized controlled trial protocol and intervention adaptation process

Details

• Alternative Title:
  Contemp Clin Trials
• Personal Author:
  McCready, Darcey ; Arem, Hannah ; Duarte, Danielle A. ; Dennis, Kyla ; Ball, Nathan ; Cafferty, Lauren A. ; Hinds, Pamela ; Howlader, Afrah ; Berg, Carla J.
• Description:
  Background:
  
  Given the increasing number of young adult cancer survivors and the impacts of cancer on various life domains, interventions addressing the psychosocial needs of young adult survivors are crucial. However, such intervention research is limited, and the existing literature has often: 1) overlooked young adult survivors’ psychosocial needs; 2) targeted depression, anxiety, or fear of recurrence – rather than positive outcomes like well-being; and 3) failed to consider scalable approaches, like digital health.
  
  Methods:
  
  This paper documents the development and refinement of an 8-week digital, coach-assisted intervention targeting hope among young adult cancer survivors (ages 18-39, within 3 years of treatment completion) and presents the protocol of the 2-arm RCT (comparing intervention vs. attention control). The intervention builds upon a 2017-2018 pilot trial (n=56); intervention refinements were based on subsequent semi-structured interviews among young adult survivors (n=23).
  
  Results:
  
  The pending trial design involves an increased sample size (n=150) to increase power and diversified recruitment efforts (i.e., clinic-based, social media, community-based organizations, etc.) to facilitate intervention reach, accessibility, and scalability. The intervention was enhanced by integrating highly relevant theoretical and therapeutic frameworks, specifically the concept of hope and Acceptance and Commitment Therapy, as well as updating intervention delivery technology. Intervention outcomes include feasibility and acceptability at end-of-treatment and preliminary efficacy on hope (primary outcome) and quality of life measures (secondary outcomes) at end-of-treatment and 16-week follow-up.
  
  Conclusions:
  
  This paper may facilitate discussion regarding approaches for addressing the significant psychosocial challenges faced by young adult survivors and catalyze dissemination of trial results.
  
  
• Subjects:
  Adolescent Adult Anxiety Cancer Survivors Depression Female Hope Humans Male Mentoring Psychosocial Intervention Quality Of Life Randomized Controlled Trials As Topic Research Design Young Adult

  More +
• Keywords:
  Acceptance And Commitment Therapy Cancer Survivorship Health Promotion Hope Positive Psychology Quality Of Life Young Adult Cancer Survivors
• Source:
  Contemp Clin Trials. 141:107545
• Pubmed ID:
  38657732
• Pubmed Central ID:
  PMC11365041
• Document Type:
  Journal Article
• Funding:
  R01 CA275066/CA/NCI NIH HHSUnited States/ ; R01 CA278229/CA/NCI NIH HHSUnited States/ ; R01 NR020608/NR/NINR NIH HHSUnited States/ ; D43 ES030927/ES/NIEHS NIH HHSUnited States/ ; R01 CA249988/CA/NCI NIH HHSUnited States/ ; R01 DA054751/DA/NIDA NIH HHSUnited States/ ; D43 TW012456/TW/FIC NIH HHSUnited States/ ; R01 CA215155/CA/NCI NIH HHSUnited States/ ; R01 TW010664/TW/FIC NIH HHSUnited States/ ; R01 CA239178/CA/NCI NIH HHSUnited States/ ; R21 CA261884/CA/NCI NIH HHSUnited States/ ; R21 NR020374/NR/NINR NIH HHSUnited States/ ; U01 DP006639/DP/NCCDPHP CDC HHSUnited States/ ; R18 HS029807/HS/AHRQ HHSUnited States/
• Volume:
  141
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:ea595c9ec0375924b7e4f9ea2df7b7cdb3b5509580ec0f08e6181865420ba2fc2d6958aa9d6cf68e246415f1224bd8c0123481a6523516124f5f33d9094d9b8e
• Download URL:
  https://stacks.cdc.gov/view/cdc/160704/cdc_160704_DS1.pdf
• File Type:
  [PDF - 121.57 KB ]