Lifetime Non-Fatal Overdose Experiences among At-risk Adolescents and Young Adults in the Emergency Department with Past-Year Opioid Use in the U.S.

Details

• Alternative Title:
  Inj Prev
• Personal Author:
  Seewald, Laura ; Bonar, Erin E. ; Bohnert, Amy S. B. ; Carter, Patrick M. ; King, Cheryl A. ; Losman, Eve D. ; Bacon, Linnea ; Wheeler, Tiffany ; Walton, Maureen A.
• Description:
  Background.
  
  Adolescents and young adults with risk factors for opioid misuse and opioid use disorder are at elevated risk for overdose. We examined prior non-fatal overdose experiences among at-risk adolescents/young adults to inform prevention efforts.
  
  Methods.
  
  Adolescents/young adults (ages 16–30) in two U.S. emergency departments self-reporting past year opioid misuse or opioid use plus a misuse risk factor completed a baseline survey as part of an ongoing randomized controlled trial. We describe baseline factors associated with a) overall non-fatal overdose experiences, and b) groups based on substance(s) used during the worst overdose experience.
  
  Results.
  
  Among 771 participants (27.9% male), 40.7% reported a non-fatal overdose experience. Compared to those without a prior overdose experience, those with prior overdose experience(s) were less likely to be heterosexual, and more likely to report a prior suicide attempt and greater peer substance misuse. Regarding the worst overdose experience, substance(s) included: 36.6% alcohol only, 28.0% alcohol and cannabis, 22.6% alcohol with other substance(s), and 12.7% other substance(s) only (e.g., opioids). Compared to the alcohol only group, the alcohol and cannabis group were younger and less likely to be heterosexual; the alcohol with other substance(s) group were older and had greater peer substance misuse; and the other substance(s) only group were more likely to be male, receive public assistance, screen positive for anxiety, and less likely to be heterosexual.
  
  Conclusions.
  
  Among at-risk adolescents/young adults, findings support the need for tailored overdose prevention efforts based on substance(s) used, with consideration of sexuality, mental health, and peer substance use.
  
  
• Subjects:
  Adolescent Adult Analgesics, Opioid Drug Overdose Emergency Service, Hospital Female Humans Male Opioid-Related Disorders Risk Factors Suicide, Attempted United States Young Adult

  More +
• Keywords:
  Alcohol Use Non-fatal Overdose Overdose Experience Substance Use
• Source:
  Inj Prev. 30(5):373-380
• Pubmed ID:
  38331586
• Pubmed Central ID:
  PMC11348801
• Document Type:
  Journal Article
• Funding:
  R49 CE003085/CE/NCIPC CDC HHSUnited States/ ; T32 HD108054/HD/NICHD NIH HHSUnited States/ ; UG3 DA050173/DA/NIDA NIH HHSUnited States/ ; UH3 DA050173/DA/NIDA NIH HHSUnited States/
• Volume:
  30
• Issue:
  5
• Collection(s):
  CDC Public Access
• Main Document Checksum:
  urn:sha-512:632973eb10a8473dcb2f915e0eff0443e54943af46a30cbacfb72f320e7beb2c40747f5b1326ebff813f2c7ca8b010c614a6c4717abfd47c279f1b445e9da524
• Download URL:
  https://stacks.cdc.gov/view/cdc/160659/cdc_160659_DS1.pdf
• File Type:
  [PDF - 145.50 KB ]