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Supplementary Material. Wastewater Surveillance for Influenza A Virus and H5 Subtype Concurrent with the Highly Pathogenic Avian Influenza A(H5N1) Virus Outbreak in Cattle and Poultry and Associated Human Cases — United States, May 12–July 13, 2024
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09/12/2024
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Source: MMWR Morb Mortal Wkly Rep.
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Alternative Title:Checklist for Jurisdictional Response to Elevated Levels of Influenza Virus and H5 Detections In Wastewater
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Description:Wastewater surveillance for influenza A viruses, including influenza A(H5) viruses, is being used to better understand the current highly pathogenic avian influenza (HPAI) A (H5N1) outbreak. Influenza A virus wastewater testing detects seasonal influenza A virus subtypes (H3N2 and H1N1) and HPAI H5N1 but does not distinguish among them nor determine if the virus was shed from a human or animal. H5-specific wastewater testing has been deployed in some sites (e.g., https://data.wastewaterscan.org/) and may expand before the start of the 2024–25 respiratory virus season. During periods of lower seasonal influenza activity, seeing increased influenza A signals in wastewater serves as a signal for additional investigation to understand the possible causes of these increases. In addition, the detection of H5 virus in a wastewater site also warrants additional investigation into possible causes. This checklist provides some context for these follow-up investigations to understand what might be causing increased influenza detections or the detection of H5 virus in wastewater and was based on early investigations for high influenza A virus levels and H5 virus wastewater signals and in collaboration with the Council for State and Territorial Epidemiologists (CSTE). To effectively review this information, it might be useful to discuss with epidemiologists and laboratorians from state and local public health, influenza program and/or HPAI team, wastewater surveillance program, and the wastewater utility.
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Pages in Document:3 Pages
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Volume:73
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Issue:37
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